Immune activation in functional dyspepsia: bystander becoming the suspect

M Ceulemans, I Jacobs, L Wauters… - Frontiers in …, 2022 - frontiersin.org
Disorders of gut-brain interaction (DGBI), formerly termed functional gastrointestinal
disorders (FGID), are highly prevalent although exact pathophysiological mechanisms …

Corticotropin-releasing factor receptor 1 (CRF-R1) antagonists: promising agents to prevent visceral hypersensitivity in irritable bowel syndrome

Y Lv, J Wen, Y Fang, H Zhang, J Zhang - Peptides, 2022 - Elsevier
Corticotropin-releasing factor (CRF) is a 41-amino acid polypeptide that coordinates the
endocrine system, autonomic nervous system, immune system, and physiological behavior …

Maternal separation induced visceral hypersensitivity evaluated via novel and small size distention balloon in post-weaning mice

E Tao, G Long, T Yang, B Chen, R Guo, D Ye… - Frontiers in …, 2022 - frontiersin.org
Early life stress (ELS) disposes to functional gastrointestinal diseases in adult, such as
irritable bowel syndrome (IBS). Maternal separation (MS) is a well-known animal model of …