Simple Summary The lack of highly specific and sensitive biomarkers for the early detection
of prostate cancer (PCa) is a major barrier to its management. Volatilomics emerged as a …

Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …

Our understanding of prostate cancer (PCa) has shifted from solely caused by a few genetic
aberrations to a combination of complex biochemical dysregulations with the prostate …

Simple Summary Prostate cancer (PCa) is a hormone-dependent tumor characterized by a
highly heterogeneous clinical outcome. This neoplastic process has become a leading …

Sarcosine has been shown to be a new biomarker for prostate cancer that is superior to
prostate-specific antigen (PSA). By detecting the concentration of sarcosine in the human …

Sp1 transcription factor regulates genes involved in various phenomena of tumor
progression. Vasculogenic mimicry (VM) is the alternative neovascularization by aggressive …

Abstract Glycine N-Methyltransferase (GNMT) is a metabolic enzyme that integrates
metabolism and epigenetic regulation. The product of GNMT, sarcosine, has been proposed …

The reprogramming of lipid metabolism and signaling pathways is the central aspect of
cancer biology. It is hypothesized that tumor cells can alter the lipid spectrum in order to fulfill …

The kynurenine metabolite is associated with many diseases and disorders, ranging from
diabetes and sepsis to more recently COVID-19. Here we report a fluorescence-based …

Motivation Breakthroughs in high-throughput technologies and machine learning methods
have enabled the shift towards multi-omics modelling as the preferred means to understand …