A systematic review of the effect of therapeutic drug monitoring on patient health outcomes during treatment with penicillins

T Luxton, N King, C Wälti, L Jeuken… - Journal of Antimicrobial …, 2022 - academic.oup.com
Background Dosing regimens guided by therapeutic drug monitoring (TDM) may be able to
improve penicillin exposure in patients, which could result in improved patient health …

DNAzyme-immobilizing microgel magnetic beads enable rapid, specific, culture-free, and wash-free electrochemical quantification of bacteria in untreated urine

R Pandey, Y Lu, E Osman, S Saxena, Z Zhang… - ACS …, 2022 - ACS Publications
Rapid, ultrasensitive, and specific detection and identification of bacteria in unprocessed
clinical specimens is critically needed to enable point-of-care diagnosis of infectious …

Therapeutic drug monitoring (TDM) in real-time: a need for the present future

I Martin-Loeches - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
Patients with severe infections are exposed to very high mortality [1]. Early suspicion and
recognition of organ failure along with effective and fast source control is the primary way to …

Emerging therapeutic drug monitoring of anti‐infective agents in Australian hospitals: availability, performance and barriers to implementation

I Sandaradura, JW Alffenaar, MO Cotta… - British journal of …, 2022 - Wiley Online Library
Aims The purpose of the study was to assess the status of emerging therapeutic drug
monitoring (TDM) of anti‐infective agents in Australian hospitals. Methods A nationwide …

Improving the tolerability of osimertinib by identifying its toxic limit

BC Agema, GDM Veerman… - Therapeutic …, 2022 - journals.sagepub.com
Background: Osimertinib is the cornerstone in the treatment of epidermal growth factor
receptor-mutated non-small cell lung cancer (NSCLC). Nonetheless,±25% of patients …

An integral pharmacokinetic analysis of piperacillin and tazobactam in plasma and urine in critically ill patients

E Wallenburg, R Ter Heine, JA Schouten… - Clinical …, 2022 - Springer
Abstract Background and Objectives Although dose optimization studies have been
performed for piperacillin and tazobactam separately, a combined integral analysis is not yet …

Therapeutic drug monitoring practices of anti-infectives: an Asia-wide cross-sectional survey

J Hou, D Marriott, D Cattaneo, S Stocker… - Frontiers in …, 2022 - frontiersin.org
Objectives: The current practice of therapeutic drug monitoring (TDM) in Asia is poorly
documented. Our aim was to capture and describe TDM services delivered in hospitals …

Impact of therapeutic drug monitoring of antibiotics in the management of infective endocarditis

G Macheda, N El Helali, G Péan de Ponfilly… - European Journal of …, 2022 - Springer
Abstract Treatment of infective endocarditis (IE) is based on high doses of antibiotics with a
prolonged duration. Therapeutic drug monitoring (TDM) allows antibiotic prescription …

Amino-functionalized Zr (IV) metal-organic polyhedron as water-stable catalyst for the photocatalytic degradation of tetracycline

H Huang, ZY Liu, SB Li, J Zhu, BX Jiang… - Journal of Solid State …, 2022 - Elsevier
In this work, an amino-functionalized Zr-based metal-organic polyhedron (denoted ZrT-1-NH
2), synthesised under the solvothermal method, has been selected as the photocatalyst for …

A Systematic review of the effect of therapeutic drug monitoring on patient health outcomes during treatment with carbapenems

TN Luxton, N King, C Wälti, LJC Jeuken, JAT Sandoe - Antibiotics, 2022 - mdpi.com
Adjusting dosing regimens based on measurements of carbapenem levels may improve
carbapenem exposure in patients. This systematic review aims to describe the effect …