[HTML][HTML] Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1
J Lin, X Wang, S Zhai, M Shi, C Peng, X Deng… - Journal of Hematology & …, 2022 - Springer
Background circRNA has been established to play a pivotal role in tumorigenesis
development in a variety of cancers; nevertheless, the biological functions and molecular …
development in a variety of cancers; nevertheless, the biological functions and molecular …
RNALigands: a database and web server for RNA–ligand interactions
RNA molecules can fold into complex and stable 3D structures, allowing them to carry out
important genetic, structural, and regulatory roles inside the cell. These complex structures …
important genetic, structural, and regulatory roles inside the cell. These complex structures …
[HTML][HTML] Interaction preferences between protein side chains and key epigenetic modifications 5-methylcytosine, 5-hydroxymethycytosine and N6-methyladenine
M Hajnic, S Alonso-Gil, AA Polyansky, A de Ruiter… - Scientific Reports, 2022 - nature.com
Covalent modifications of standard DNA/RNA nucleobases affect epigenetic regulation of
gene expression by modulating interactions between nucleic acids and protein readers. We …
gene expression by modulating interactions between nucleic acids and protein readers. We …
Computational methods for predicting hotspots at protein–RNA interfaces
LC Mei, GF Hao, GF Yang - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Protein–RNA interactions play essential roles in many critical biological events. A
comprehensive understanding of the mechanisms underlying these interactions is helpful …
comprehensive understanding of the mechanisms underlying these interactions is helpful …
蛋白质-DNA 复合物中残基界面偏好性分析及在识别界面中的应用
杨爽, 李春华 - Biophysics, 2022 - hanspub.org
蛋白质-DNA 识别在生物过程中起着重要作用, 其结合是由序列特异性识别和结构特征共同影响
的. 为了研究残基类型和蛋白质二级结构对结合的贡献, 本文构建了一个新的非冗余蛋白质-DNA …
的. 为了研究残基类型和蛋白质二级结构对结合的贡献, 本文构建了一个新的非冗余蛋白质-DNA …
[PDF][PDF] Matea Hajnic1, 2, Santiago Alonso Gil1, Anton A. Polyansky1, Anita de Ruiter1, 3 &
B Zagrovic1Ε - Scientific Reports, 2022 - researchgate.net
Covalent modifications of standard DNA/RNA nucleobases affect epigenetic regulation of
gene expression by modulating interactions between nucleic acids and protein readers. We …
gene expression by modulating interactions between nucleic acids and protein readers. We …
Advanced computational tools for quantitative analysis of protein–nucleic acid interfaces
S Mukherjee, C Nithin - Advances in Protein Molecular and Structural …, 2022 - Elsevier
Protein–nucleic acids interactions, which involve the binding of protein with RNA or/and
DNA molecules, play crucial roles in many biochemical pathways. Experimental studies of …
DNA molecules, play crucial roles in many biochemical pathways. Experimental studies of …
[HTML][HTML] Statistical potentials for RNA-protein interactions optimized by CMA-ES
T Kimura, N Yasuo, M Sekijima, B Lustig - Journal of Molecular Graphics …, 2022 - Elsevier
Characterizing RNA-protein interactions remains an important endeavor, complicated by the
difficulty in obtaining the relevant structures. Evaluating model structures via statistical …
difficulty in obtaining the relevant structures. Evaluating model structures via statistical …
[PDF][PDF] Homology modeling of the complex between the Repressor of Primer protein and its cognate RNA kissing complex
D Nikolopoulou - 2022 - utopia.duth.gr
The ROP protein is a dimeric protein with an α-helix bundle conformation that is found in
bacteria. ROP protein is involved in the replication regulation mechanism of the …
bacteria. ROP protein is involved in the replication regulation mechanism of the …