Background circRNA has been established to play a pivotal role in tumorigenesis
development in a variety of cancers; nevertheless, the biological functions and molecular …

RNA molecules can fold into complex and stable 3D structures, allowing them to carry out
important genetic, structural, and regulatory roles inside the cell. These complex structures …

Covalent modifications of standard DNA/RNA nucleobases affect epigenetic regulation of
gene expression by modulating interactions between nucleic acids and protein readers. We …

Protein–RNA interactions play essential roles in many critical biological events. A
comprehensive understanding of the mechanisms underlying these interactions is helpful …

蛋白质-DNA 识别在生物过程中起着重要作用, 其结合是由序列特异性识别和结构特征共同影响
的. 为了研究残基类型和蛋白质二级结构对结合的贡献, 本文构建了一个新的非冗余蛋白质-DNA …

Covalent modifications of standard DNA/RNA nucleobases affect epigenetic regulation of
gene expression by modulating interactions between nucleic acids and protein readers. We …

Protein–nucleic acids interactions, which involve the binding of protein with RNA or/and
DNA molecules, play crucial roles in many biochemical pathways. Experimental studies of …

Characterizing RNA-protein interactions remains an important endeavor, complicated by the
difficulty in obtaining the relevant structures. Evaluating model structures via statistical …

The ROP protein is a dimeric protein with an α-helix bundle conformation that is found in
bacteria. ROP protein is involved in the replication regulation mechanism of the …