Multi-scale analysis of the foaming mechanism in anaerobic digestion of food waste: From physicochemical parameter, microbial community to metabolite response

P Yang, Y Peng, H Liu, D Wu, R Yuan, X Wang, L Li… - Water Research, 2022 - Elsevier
Foaming is a key issue that threatens the efficient and stable operation of the anaerobic
digestion process. This study introduced three disturbances to induce foaming and explored …

[HTML][HTML] Coenzyme A-dependent tricarboxylic acid cycle enzymes are decreased in Alzheimer's disease consistent with cerebral pantothenate deficiency

C Sang, SA Philbert, D Hartland, RD Unwin… - Frontiers in aging …, 2022 - frontiersin.org
Sporadic Alzheimer's disease (sAD) is the commonest cause of age-related
neurodegeneration and dementia globally, and a leading cause of premature disability and …

[HTML][HTML] Elevated cerebrospinal fluid glucose levels and diabetes mellitus are associated with activation of the neurotoxic polyol pathway

C Tigchelaar, ML van Zuylen, AH Hulst, B Preckel… - Diabetologia, 2022 - Springer
Aims/hypothesis During hyperglycaemia, some glucose bypasses glycolysis and is
metabolised via the potentially neurotoxic polyol pathway, in which glucose is metabolised …

Effect of normal and strict anaerobic fermentation on physicochemical quality and metabolomics of yogurt

R Ding, M Li, Y Zou, Y Wang, C Yan, H Zhang, R Wu… - Food Bioscience, 2022 - Elsevier
Generally, yogurts on the market are usually anaerobic fermentation, but oxygen can be still
dissolved in the production process, which is actually not strict anaerobic. This study …

[HTML][HTML] Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

M Lunghi, J Kloehn, A Krishnan, E Varesio… - Nature …, 2022 - nature.com
Coenzyme A (CoA) is an essential molecule acting in metabolism, post-translational
modification, and regulation of gene expression. While all organisms synthesize CoA, many …

[HTML][HTML] Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats

AN Zul Aznal, NA Mohamad Nor Hazalin… - Frontiers in …, 2022 - frontiersin.org
Adolescence is a critical developmental period during which exposure to psychoactive
substances like kratom (Mitragyna speciosa) can cause long-lasting deleterious effects …

Association of vitamins and neurotransmitters: understanding the effect on schizophrenia

V Bansal, I Chatterjee - Neurochemical Journal, 2022 - Springer
One of the most challenging tasks is identifying all the chemical interactions inside the
human body. The interplay of vitamins and neurotransmitters is an intriguing topic to study to …

The relationships between neuroglial and neuronal changes in Alzheimer's disease, and the related controversies II: gliotherapies and multimodal therapy

A Toledano-Díaz, MI Alvarez… - Journal of Central …, 2022 - journals.sagepub.com
Since the original description of Alzheimer´ s disease (AD), research into this condition has
mainly focused on assessing the alterations to neurons associated with dementia, and those …

[HTML][HTML] Treatment of Alzheimer's disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review

Z Liu, R Guan, F Bu, L Pan - Medicine, 2022 - journals.lww.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by
neurodegeneration, nerve loss, neurofibrillary tangles, and Aβ plaques. In modern medical …

Crystallographic and biophysical analyses of Pseudomonas aeruginosa ketopantoate reductase: Implications of ligand induced conformational changes in cofactor …

A Choudhury, B Khanppnavar, S Datta - Biochimie, 2022 - Elsevier
Ketopantoate reductases (KPRs) catalyse NADPH-dependent reduction of ketopantoate to
pantoate, the rate-limiting step of pantothenate biosynthetic pathway. In our recent study, we …