The role of Toll-like receptors and neuroinflammation in Parkinson's disease
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …
Lactobacillus johnsonii alleviates colitis by TLR1/2-STAT3 mediated CD206+ macrophagesIL-10 activation
Imbalance of gut microbiota homeostasis is related to the occurrence of ulcerative colitis
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …
[HTML][HTML] Toll-like receptor 1 locus re-examined in a genome-wide association study update on anti–Helicobacter pylori IgG titers
SY Lam, MC Mommersteeg, B Yu, L Broer… - Gastroenterology, 2022 - Elsevier
Background & Aims A genome-wide significant association between anti–Helicobacter
pylori (H pylori) IgG titers and Toll-like receptor (TLR1/6/10) locus on 4p14 was …
pylori (H pylori) IgG titers and Toll-like receptor (TLR1/6/10) locus on 4p14 was …
Conversion of lignin-derived 3-methoxycatechol to the natural product purpurogallin using bacterial P450 GcoAB and laccase CueO
S Zhang, X Wu, Y Xiao - Applied Microbiology and Biotechnology, 2022 - Springer
Purpurogallin is a natural benzotropolone extracted from Quercus spp, which has
antioxidant, anticancer, and anti-inflammatory properties. Purpurogallin is typically …
antioxidant, anticancer, and anti-inflammatory properties. Purpurogallin is typically …
Toll-like receptors in the mechanism of tributyltin-induced production of pro-inflammatory cytokines, IL-1β and IL-6
A Alcala, B Osborne, B Allen, A Seaton-Terry… - Toxicology, 2022 - Elsevier
Tributyltin (TBT) is an environmental contaminant due to its use in a variety of applications
as a biocide, including in marine anti-fouling paints. It has been detected in a number of …
as a biocide, including in marine anti-fouling paints. It has been detected in a number of …
Membrane Vesicles Derived From Clostridium botulinum and Related Clostridial Species Induce Innate Immune Responses via MyD88/TRIF Signaling in vitro
N Kobayashi, K Abe, S Akagi, M Kitamura… - Frontiers in …, 2022 - frontiersin.org
Clostridium botulinum produces botulinum neurotoxin complexes that cause botulism.
Previous studies elucidated the molecular pathogenesis of botulinum neurotoxin complexes; …
Previous studies elucidated the molecular pathogenesis of botulinum neurotoxin complexes; …
Toll-like Receptor 2 is Involved in Calcium Influx and Acrosome Reaction to Facilitate Sperm Penetration to Oocytes During in vitro Fertilization in Cattle
Cumulus cells of ovulated cumulus-oocyte complexes (COCs) express Toll-like receptor 2
(TLR2), pathogen recognition receptors, to recognize and react to sperm signals during …
(TLR2), pathogen recognition receptors, to recognize and react to sperm signals during …
[HTML][HTML] Transcriptomic profiling of clobetasol propionate-induced immunosuppression in challenged zebrafish embryos
F Essfeld, H Reinwald, G Salinas, C Schäfers… - Ecotoxicology and …, 2022 - Elsevier
In the ecotoxicological hazard assessment of chemicals, the detection of immunotoxicity is
currently neglected. This is mainly due to the complexity of the immune system and the …
currently neglected. This is mainly due to the complexity of the immune system and the …
Syntheses of 7‐, 8‐and 9‐Bromobenzotropolone, Cross‐Couplings of Their Methyl Ethers, and Deprotection to 7‐, 8‐or 9‐Substituted Benzotropolones
P Koblischek, R Brückner - European Journal of Organic …, 2022 - Wiley Online Library
Abstract Unprotected 6, 7‐benzotropolone and bromine were known to undergo an
electrophilic substitution delivering the 7‐bromo derivative; it was carried on as its methyl …
electrophilic substitution delivering the 7‐bromo derivative; it was carried on as its methyl …
Acid‐dependent Divergent Conversion of ortho‐Arylcyclopropanecarbonyl Carboxaldehydes for the Synthesis of Furanodibenzocycloheptenes and …
N Palavong, J Jantrapirom, J Tummatorn… - Asian Journal of …, 2022 - Wiley Online Library
Abstract ortho‐Arylcyclopropanecarbonyl carboxaldehydes were utilized common
substrates for the synthesis of furanodibenzocycloheptenes and dibenzocycloheptenes …
substrates for the synthesis of furanodibenzocycloheptenes and dibenzocycloheptenes …