Cardiovascular therapeutics: A new potential for anxiety treatment?

K Repova, S Aziriova, K Krajcirovicova… - Medicinal Research …, 2022 - Wiley Online Library
Besides the well‐recognized risk factors, novel conditions increasing cardiovascular
morbidity and mortality are emerging. Undesirable emotions and behavior such as anxiety …

[HTML][HTML] Brain-penetrant calcium channel blockers are associated with a reduced incidence of neuropsychiatric disorders

L Colbourne, PJ Harrison - Molecular Psychiatry, 2022 - nature.com
Calcium channel blockers (CCBs) differ in their ability to penetrate into the brain.
Pharmacoepidemiological studies suggest that CCBs as a class may have beneficial effects …

Vascular dysfunction and increased cardiovascular risk in hypospadias

AK Lucas-Herald, AC Montezano… - European heart …, 2022 - academic.oup.com
Aims Hypogonadism is associated with cardiovascular disease. However, the
cardiovascular impact of hypogonadism during development is unknown. Using …

Calcium channel antagonists for mood disorders

SL Dubovsky, D Marshall - Journal of Clinical …, 2022 - journals.lww.com
Purpose Development of new thymoleptic medications has primarily centered on
anticonvulsants and antipsychotic drugs. Based on our studies of intracellular calcium ion …

Retinal Microvascular Caliber and Incident Depressive Symptoms: The Multi-Ethnic Study of Atherosclerosis

ACE Van Gennip, S Sedaghat… - American journal of …, 2022 - academic.oup.com
Cerebral microvascular dysfunction may contribute to depression via disruption of brain
structures involved in mood regulation, but evidence is limited. The retina allows for …

Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers and risk of depression among older people with hypertension

TT van Sloten, PC Souverein… - Journal of …, 2022 - journals.sagepub.com
Background: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor
blockers (ARBs), commonly used antihypertensive drugs, may have a protective effect …

[HTML][HTML] Associations of cardiovascular agents and metformin with depression symptoms: a cross-sectional analysis from the HUNT Study, Norway

I Bojanić, O Bjerkeset, LJ Williams, M Berk… - Drugs-Real World …, 2022 - Springer
Background Cardiovascular agents, including angiotensin-converting enzyme inhibitors,
angiotensin II receptor inhibitors, acetylsalicylic acid, statins, and metformin, have …

[HTML][HTML] Риск развития сердечно-сосудистых заболеваний при биполярном расстройстве. Биологические факторы и терапия

СН Мосолов, ЕЮ Федорова - Терапевтический архив, 2022 - cyberleninka.ru
Обоснование. Биполярное расстройство (БР)-одно из наиболее распространенных
психических расстройств, которое характеризуется чередованием эпизодов …

[HTML][HTML] CACNA1C (CaV1. 2) and other L-type calcium channels in the pathophysiology and treatment of psychiatric disorders: Advances from functional genomics …

PJ Harrison, SM Husain, H Lee, A De Los Angeles… - …, 2022 - Elsevier
A role for voltage-gated calcium channels (VGCCs) in psychiatric disorders has long been
postulated as part of a broader involvement of intracellular calcium signalling. However, the …

Can β-blockers influence regular daily physical activity?

ML Alimento, P Palermo, G Italiano… - Journal of …, 2022 - journals.lww.com
Background: In hypertension, β-blockers have a high rate of nonadherence to treatment
likely because of fatigue. Methods: We evaluate daily physical activity and maximal exercise …