New insights for biosensing: Lessons from microbial defense systems

Y Wan, C Zong, X Li, A Wang, Y Li, T Yang… - Chemical …, 2022 - ACS Publications
Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …

Ultrafast real-time pcr in photothermal microparticles

BK Kim, SA Lee, M Park, EJ Jeon, MJ Kim, JM Kim… - ACS …, 2022 - ACS Publications
As the turnaround time of diagnosis becomes important, there is an increasing demand for
rapid, point-of-care testing (POCT) based on polymerase chain reaction (PCR), the most …

Micro-PCR chip-based multifunctional ultrafast SARS-CoV-2 detection platform

H Yin, Z Tong, C Shen, X Xu, H Ma, Z Wu, Y Qi, H Mao - Lab on a Chip, 2022 - pubs.rsc.org
When dealing with infectious pathogens, the point-of-care screening and diagnosis strategy
should be low-cost, simple, rapid and accurate. Here, we report a multifunctional rapid PCR …

SF-qPCR: strand displacement-based fast quantitative polymerase chain reaction

J Kim, C Jung - BioChip Journal, 2022 - Springer
Nucleic acid testing (NAT) is important for the identification and quantification of specific
nucleic acid targets, both DNA and RNA, in life sciences and clinical diagnostics. Nucleic …

Simulation of Rapid Thermal Cycle for Ultra-Fast PCR

Z Yang, J Zhang, X Tong, W Li, L Liang, B Liu, C Chen - Sensors, 2022 - mdpi.com
The polymerase chain reaction (PCR) technology is a mainstream detection method used in
medical diagnoses, environmental monitoring, food hygiene, and safety. However, the …

Modeling heat losses in microfluidic devices: The case of static chamber devices for DNA amplification

VE Papadopoulos, IN Kefala, GD Kaprou… - International Journal of …, 2022 - Elsevier
Most of the functions integrated in lab-on-a-chip (LoC) systems require the heating and
cooling of samples in order to activate specific reactions. A common example in LoC …

A point-of-care device for fully automated, fast and sensitive protein quantification via qPCR

FR Cavallo, KB Mirza, S de Mateo, L Miglietta… - Biosensors, 2022 - mdpi.com
This paper presents a fully automated point-of-care device for protein quantification using
short-DNA aptamers, where no manual sample preparation is needed. The device is based …

[HTML][HTML] Validation of a point-of-need diagnostic tool for rapid diagnosis of norovirus gastroenteritis

RP Janapatla, CC Lee, A Dudek, CH Chuang… - Pediatrics & …, 2022 - Elsevier
Background The genogroups GI and GII of norovirus (NoV) ribonucleic acid (RNA) genetic
variants are the most prevalent cause of acute gastroenteritis outbreaks, especially in …

A Review on PCR and POC-PCR-A Boon in the Diagnosis of COVID-19

S Sindhuja, S Amuthalakshmi… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Since the global spread of covid-19, PCR predominantly has taken the lead in the diagnosis.
It amplifies a particular DNA target sequence into millions of copies. To simplify the …

A platform for high-bandwidth, low-noise electrical nanopore sensing with thermal control

D Lomovtsev - 2022 - ruor.uottawa.ca
Solid-state nanopores are an emerging class of single-molecule detectors that provide
information about molecular identity via the analysis of transient fluctuations in the ionic …