Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …

It is well‏‏ established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …

Diabetic foot ulceration (DFU) is a devastating complication of diabetes whose pathogenesis
remains incompletely understood. Here, we profile 174,962 single cells from the foot …

Diabetic foot ulceration is a devastating diabetic complication with unmet needs. We
explored the efficacy of calcium-crosslinked alginate dressings in topically delivering …

Monocytes and lymphocytes play a key role in physiologic wound healing and might be
involved in the impaired mechanisms observed in diabetes. Skin wound macrophages are …

Macrophages are essential immune cells and play a major role in the immune response as
pro-inflammatory or anti-inflammatory agents depending on their plasticity and functions …

Macrophage differentiation and polarization are essential players in the success of the
wound-healing process. Acute simple wounds progress from inflammation to proliferation …

Macrophages regulate cutaneous wound healing by immune surveillance, tissue repair and
remodelling. The depletion of dermal macrophages during the early and middle stages of …

Biomaterial–immune system interactions play an important role in postimplantation
osseointegration to retain the functionality of healthy and intact bones. Therefore …

Inflammation is a life-saving immune reaction occurring in response to invading pathogens.
Nonetheless, inflammation can also occur in an uncontrolled, unrestricted manner, leading …