Chemotherapy induced gastrointestinal toxicities

HI Akbarali, KH Muchhala, DK Jessup… - Advances in cancer …, 2022 - Elsevier
Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …

Thymol ameliorates 5‐fluorouracil‐induced intestinal mucositis: Evidence of down‐regulatory effect on TGF‐β/MAPK pathways through NF‐κB

LA Al‐Khrashi, AM Badr, MA AL‐Amin… - … of Biochemical and …, 2022 - Wiley Online Library
Fluorouracil (5‐FU) is a front‐line cytotoxic therapy. However, intestinal mucositis is a well‐
known adverse event of 5‐FU, which limits its therapeutic use. Indeed, thymol, which is a …

Impact of systemic dexamethasone administration on oral mucositis induced by anthracycline-containing regimens in breast cancer treatment

Y Saito, Y Takekuma, T Takeshita, T Oshino… - Scientific reports, 2022 - nature.com
Oral mucositis (OM) is one of the most common complications associated with
chemotherapy. Here, we evaluated whether systemic dexamethasone (DEX) dosage in …

A randomized, placebo-controlled study to evaluate the effect of bio-enhanced turmeric formulation on radiation-induced oral mucositis

TP Soni, AK Gupta, LM Sharma, H Singhal, S Sharma… - Orl, 2022 - karger.com
Introduction: Oral mucositis is the most common toxicity of chemoradiotherapy treatment of
head and neck cancers. The present study was performed to evaluate the effect of a …

Does photobiomodulation affects CK10 and CK14 in oral mucositis radioinduced repair?

AVN Sardo, MF Andrade, A Figueiredo… - International Journal of …, 2022 - mdpi.com
The mechanisms of action of photobiomodulation (PBM) in oral mucositis (OM) are not
completely elucidated. To enlighten the role of PBM in the evolution of epithelial maturity in …

Investigation of the protective effect of gel incorporating Eugenia jambolana leaf extract on 5-fluorouracil-induced oral mucositis: an animal study

N Aksoy, E Sen, S Sukmasari, ÖB Özakpınar… - Journal of cancer …, 2022 - Springer
Purpose The study aimed to evaluate the possible preventive effect of two concentrations (3
and 5% w/w) of Eugenia jambolana (EJ) extract against 5-FU-induced mucositis. Method …

[PDF][PDF] A REVIEW: CURRENT APPROACHES TO MANAGEMENT OF ETIOPATHOGENESIS OF MUCOSITIS

S Singh, P Khanduri, S Singh - 2022 - wjpr.s3.ap-south-1.amazonaws.com
Inflammation reaction of epithelial mucosa to chemo-radiotherapy cytotoxic impacts prompts
mucositis, a difficult result of antineoplastic medicines. Around 40% of the patients treated …

Role of Map Kinase Phosphatase-1 in Radiation-Induced Oral Mucositis

CL Kirkwood - 2022 - search.proquest.com
Abstract Introduction: Mitogen Activating Protein (MAPK) kinase phosphatase-1 (MKP-1),
encoded by Dusp (Dual specificity protein phosphatase)-1, is a well-characterized negative …

Laser de baixa intensidade no tratamento de mucosite oral induzida por radiação: avaliação imunohistoquímica com marcadores de citoqueratinas CK 10 e CK 14

AVN Sardo - teses.usp.br
A mucosite oral (MO) é uma lesão frequente em pacientes oncológicos e que pode ser
causada tanto por radioterapia em região de cabeça e pescoço ou por certos …

[引用][C] Yoshitaka Saito1, Yoh Takekuma1, Takashi Takeshita2, Tomohiro Oshino2 &

M Sugawara - Scientific Reports, 2022