Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

Metabolic associated fatty liver disease (MAFLD) is one of the most common causes of
chronic liver disease worldwide. To date, there is no FDA-approved treatment, so there is an …

This study aimed to investigate the therapeutic effects of nobiletin (NOB) on nonalcoholic
steatohepatitis (NASH) and liver fibrosis in mice and to elucidate its underlying molecular …

Ovarian cancer ranks fifth in terms of cancer mortality in women due to lack of early
diagnosis and poor clinical management. Characteristics like high cellular proliferation, EMT …

Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk
for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its …

The Omicron variant (B. 529) of COVID-19 caused disease outbreaks worldwide because of
its contagious and diverse mutations. To reduce these outbreaks, therapeutic drugs and …

Oxidative stress is a crucial factor in the development of various liver diseases. Irisin, a
metabolic hormone discovered in 2012, is mainly produced by proteolytic cleavage of …

Type 2 diabetes mellitus (T2DM) is associated with cardiovascular disease (CVD) and
sodium glucose cotransporter 2 inhibitors, as oral medications for T2DM treatment have …

Alzheimerʼs disease (AD), an age‐related neurodegenerative disease, is a striking global
health problem. Ferroptosis is a newly discovered form of cell death characterized by iron …

Reduced feed intake during the transition period renders cows unable to meet their energy
needs for maintenance and lactation, leading to a state of negative energy balance. Severe …