[HTML][HTML] Development of pharmaceutical nanomedicines: from the bench to the market

AA Halwani - Pharmaceutics, 2022 - mdpi.com
Nanotechnology plays a significant role in the field of medicine and in drug delivery, mainly
due to the major limitations affecting the conventional pharmaceutical agents, and older …

[HTML][HTML] Current understanding of hexavalent chromium [Cr (VI)] neurotoxicity and new perspectives

JP Wise Jr, JL Young, J Cai, L Cai - Environment international, 2022 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a global environmental pollutant that increases
risk for several types of cancers and is increasingly being recognized as a neurotoxicant …

[HTML][HTML] Cerebral iron deposition in neurodegeneration

P Dusek, T Hofer, J Alexander, PM Roos, JO Aaseth - Biomolecules, 2022 - mdpi.com
Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

[HTML][HTML] Alzheimer's disease: treatment strategies and their limitations

E Passeri, K Elkhoury, M Morsink, K Broersen… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is the most frequent case of neurodegenerative disease and is
becoming a major public health problem all over the world. Many therapeutic strategies …

Synthesis of metal nanoclusters and their application in Hg2+ ions detection: a review

G Panthi, M Park - Journal of Hazardous Materials, 2022 - Elsevier
Abstract Mercuric (Hg 2+) ions released from human activities, natural phenomena, and
industrial sources are regarded as the global pollutant of world's water. Hg 2+ ions …

[HTML][HTML] Neurodegenerative diseases: implications of environmental and climatic influences on neurotransmitters and neuronal hormones activities

EA Ayeni, AM Aldossary, DA Ayejoto… - International Journal of …, 2022 - mdpi.com
Neurodegenerative and neuronal-related diseases are major public health concerns.
Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal …

Influence of heavy metals in Parkinson's disease: an overview

B Vellingiri, A Suriyanarayanan, KS Abraham… - Journal of …, 2022 - Springer
Parkinson's disease (PD) is an ageing disorder with deterioration of dopamine neurons
which leads to motor complications like tremor, stiffness, slow movement and postural …

Current status and future directions for a neurotoxicity hazard assessment framework that integrates in silico approaches

KM Crofton, A Bassan, M Behl, YG Chushak… - Computational …, 2022 - Elsevier
Neurotoxicology is the study of adverse effects on the structure or function of the developing
or mature adult nervous system following exposure to chemical, biological, or physical …

[HTML][HTML] Nanomedicine in the face of Parkinson's disease: from drug delivery systems to nanozymes

The complexity and overall burden of Parkinson's disease (PD) require new
pharmacological approaches to counteract the symptomatology while reducing the …

Association of autism with toxic metals: A systematic review of case-control studies

CN Amadi, CN Orish, C Frazzoli… - … Biochemistry and Behavior, 2022 - Elsevier
Environmental factors have been associated with the etiology of autism spectrum disorder
ASD in recent times. The involvement of toxic metals in the generation of reactive oxygen …