A critical review of chloroquine and hydroxychloroquine as potential adjuvant agents for treating people with cancer
Chloroquine (CQ) and hydroxychloroquine (HCQ) have been used to treat malaria and
autoimmune diseases for more than 70 years; they also have immunomodulatory and …
autoimmune diseases for more than 70 years; they also have immunomodulatory and …
Discovery of a benzimidazole-based dual FLT3/TrKA inhibitor targeting acute myeloid leukemia
FMS-like tyrosine kinase 3 (FLT3) enzyme overexpression and mutations are the most
common molecular abnormalities associated with acute myeloid leukemia (AML). In …
common molecular abnormalities associated with acute myeloid leukemia (AML). In …
Discovery of EMD37, a 1, 2, 4-oxadiazole derivative, as a novel endoplasmic reticulum stress inducer with potent anticancer activity
Targeting endoplasmic reticulum (ER) stress presents a promising strategy in cancer
therapy. We previously reported a series of 1, 2, 4-oxadiazole derivatives that induced the …
therapy. We previously reported a series of 1, 2, 4-oxadiazole derivatives that induced the …
Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno [2, 3-d] pyrimidine-based EGFR …
SN Milik, AK Abdel-Aziz, MM El-Hendawy… - Journal of Molecular …, 2022 - Elsevier
EGFR inhibitors have been in clinical use for the treatment of non-small cell lung cancer and
breast cancer for years. However, generation after generation of the developed EGFR …
breast cancer for years. However, generation after generation of the developed EGFR …
Blockade of uttroside b-induced autophagic pro-survival signals augments its chemotherapeutic efficacy against hepatocellular carcinoma
Our previous study has demonstrated that Uttroside B (Utt-B), a saponin isolated from the
leaves of Solanum nigrum Linn induces apoptosis in hepatic cancer cells and exhibits a …
leaves of Solanum nigrum Linn induces apoptosis in hepatic cancer cells and exhibits a …
Clinical approaches in targeting ROS-induced cancer
Reactive oxygen species (ROS) results from various metabolic processes and plays a
significant role as secondary messengers across multiple signaling pathways. However, any …
significant role as secondary messengers across multiple signaling pathways. However, any …
Identification of novel furo [2, 3-d] pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluation
Various substituted synthetic chalcones demonstrated potent anti-cancer activities. In the
current study a series of novel furo [2, 3-d] pyrimidine based chalcones were synthesized as …
current study a series of novel furo [2, 3-d] pyrimidine based chalcones were synthesized as …
Investigating the anti-tumoral effect of yarrow (Achillea milllefolium) on the mice in which ehrlich solid tumor is created
G Bağcı Uzun, M Nisari, A Hanım Yay… - Medical Oncology, 2022 - Springer
In this study, BALB/c mice with Ehrlich solid tumors were used to examine the effect of
Achillea millefolium L.(AM) extract on the Ehrlich ascites tumor (EAT) model, which is one of …
Achillea millefolium L.(AM) extract on the Ehrlich ascites tumor (EAT) model, which is one of …
Autophagy Regulates the Antiangiogenic Property of the Multikinase Inhibitor Lenvatinib in Human Papillary Thyroid Cancer Cells
L Xue - 2022 - search.proquest.com
Background: Thyroid cancer is the most common cancer of the human head and neck
region, and its incidence rate has dramatically increased during the last three decades …
region, and its incidence rate has dramatically increased during the last three decades …
[引用][C] مطالعه اثر Silibinin و Quercetin بر روی اثر متقابل هیپرگلیسمی و اتوفاژی در سلولهای ورید بند ناف انسان
رضابخش, آیسا - دانشگاه علوم پزشکی تبریز، دانشکده …