The first bioprocess that occurs in response to wounding is the deterrence of local
hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis …

Platelets are blood cells that are primarily produced by the shedding of megakaryocytes in
the bone marrow. Platelets participate in a variety of physiological and pathological …

Treatment of bleeding disorders using transfusion of donor-derived platelets faces logistical
challenges due to their limited availability, high risk of contamination, and short (5 to 7 days) …

Nanobiotechnology and nanomedicine are rapidly growing fields, in which nanomaterials
(NMs) can lead to enhanced therapeutic efficacy by achieving efficient transport and drug …

Uncontrollable hemorrhage remains staple trouble in surgical procedures and a leading
cause after major trauma. The bleeding issue may trigger various pathologic scenarios that …

Cancer nanomedicines are designed to encapsulate different therapeutic agents, prevent
their premature release, and deliver them specifically to cancer cells, due to their ability to …

Background: Titanium (Ti) is one of the most popular implant materials, and its surface
titanium dioxide (TiO2) provides good biocompatibility. The coagulation of blood on Ti …

The present invention relates to prevention and/or treatment of infection by a platelet-
targeting microbe in a subject. The present invention provides for methods, combinations …

OBJECTIVE To assess the safety and efficacy of the platelet-like nanoparticle (PLN), and to
assess its safety in repeated administration. ANIMALS 6 purpose-bred dogs …

Abstract Purpose of Review To review the role of platelet transfusion in resuscitation for
trauma, including normal platelet function and alterations in behavior following trauma …