Brain disorders are characterized by the progressive loss of structure and function of the
brain as a consequence of progressive degeneration and/or death of nerve cells. Aging is a …

Developmental signalling pathways such as Wnt/β-catenin, Notch and Sonic hedgehog play
a central role in nearly all the stages of neuronal development. The term 'embryonic'might …

Metabolic flexibility is a hallmark of many cancers where mitochondrial respiration is
critically involved, but the molecular underpinning of mitochondrial control of cancer …

As a prototypical proinflammatory cytokine, interleukin-1 (IL-1) exacerbates the early post-
stroke inflammation, whereas its neutralization is protective. To further investigate the …

Objectives Natural borneol and synthetic borneol were commonly used to treat ischaemic
stroke in clinical practice. This study evaluated their different neuroprotective effects on the …

Background & aim Diabetic foot ulcers are major cause of lower limb amputations in the
diabetic population. The major factors that play a role in causing the delay of the process of …

Although stroke is one of the world's leading causes of death and disability, and more than a
thousand candidate neuroprotective drugs have been proposed based on extensive in vitro …

DJ-1 plays a neuroprotective role in cerebral ischemia-reperfusion (I/R) injury and
participates in the apoptosis of brain nerve cells, but the underlying mechanism is unclear …

OBJECTIVE: Lycium barbarum polysaccharide (LBP) is the efficient primary compound of
Lycium barbarum and has been shown to alleviate hyperglycemia-aggravated cerebral …

Although stroke is one of the world's leading causes of death and disability, and more than a
thousand candidate neuroprotective drugs have been proposed based on extensive in vitro …