The aim of this review is to explore how metabolic changes induced by diets high in
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …

Behavioral models are central to behavioral neuroscience. To study the neural mechanisms
of maladaptive behaviors (including binge eating and drug addiction), it is essential to …

Food addiction is characterized by a loss of behavioral control over food intake and is
associated with obesity and other eating disorders. The mechanisms underlying this …

This review aims to draw attention to current studies on syndromes related to food eating
behavior, including food addiction, and to highlight the neurobiological and …

Rates of obesity and obesity-associated diseases have increased dramatically in countries
with developed economies. Substance use disorders (SUDs) are characterized by the …

Methamphetamine (meth) causes enduring changes within the medial prefrontal cortex
(mPFC) and the nucleus accumbens (NA). Projections from the mPFC to the NA have a …

Rationale Attempts to lose weight often fail despite knowledge of the health risks associated
with obesity and determined efforts. We previously showed that rodents fed an obesogenic …

Bariatric surgery results in long-term weight loss and an improved metabolic phenotype due
to changes in the gut-brain axis regulating appetite and glycaemia. Neuroendocrine …

To find food efficiently, a hungry animal engages in goal-directed behaviors that rely on
nucleus accumbens (NAc) circuits. Synaptic alterations within these circuits underlie shifts in …

A loss of neuroplastic control on nucleus accumbens (NAc) neuronal activity exerted by the
medial prefrontal cortex (mPFC) through long-term depression (LTD) is involved in triggering …