Antimicrobial resistance (AMR) is a grand societal challenge with important dimensions in
the water environment that contribute to its evolution and spread. Environmental monitoring …

A meta-analysis of 94 published studies was conducted to explore the impacts of farmland
application of antibiotic-contaminated manures on antibiotic concentrations and ARG …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …

Microbial genes encode the majority of the functional repertoire of life on earth. However,
despite increasing efforts in metagenomic sequencing of various habitats,–, little is known …

Integrons are flexible gene-exchanging platforms that contain multiple cassettes encoding
accessory genes whose order is shuffled by a specific integrase. Integrons embedded within …

The human gut microbiome plays an important role in health, but its archaeal diversity
remains largely unexplored. In the present study, we report the analysis of 1,167 …

Glaciers represent a unique inventory of microbial genetic diversity and a record of
evolution. The Tibetan Plateau contains the largest area of low-latitude glaciers and is …

The gut microbiomes of human populations worldwide have many core microbial species in
common. However, within a species, some strains can show remarkable population …

Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …