[HTML][HTML] Head and neck squamous cell carcinoma in elderly patients: role of radiotherapy and chemotherapy

M Fasano, I D'Onofrio, MP Belfiore, A Angrisani… - Cancers, 2022 - mdpi.com
Simple Summary The focus of this review deals with the management of elderly patients with
head and neck squamous cell carcinoma, discussing the role of clinical management …

Impact of comprehensive geriatric assessment on the risk of adverse events in the older patients receiving anti-cancer therapy: a systematic review and meta-analysis

MH Chuang, JY Chen, WW Tsai, CW Lee… - Age and …, 2022 - academic.oup.com
Background to assess the efficacy of comprehensive geriatric assessment (CGA) for
preventing treatment-related toxicity in older people undergoing non-surgical cancer …

The use and knowledge of validated geriatric assessment instruments among US community oncologists

A Gajra, Y Jeune-Smith, S Fortier, B Feinberg… - JCO Oncology …, 2022 - ascopubs.org
PURPOSE: The use of a standardized geriatric assessment (GA) to inform treatment
decisions in older adults with cancer improves quality of life, reduces treatment-related …

[HTML][HTML] Randomized controlled trial of geriatric consultation versus standard care in older adults with hematologic malignancies

C DuMontier, H Uno, T Hshieh, G Zhou, R Chen… - …, 2022 - ncbi.nlm.nih.gov
We conducted a randomized controlled trial in older adults with hematologic malignancies to
determine the impact of geriatrician consultation embedded in our oncology clinic alongside …

Efficient Magnetic Nanocatalyst-Induced Chemo- and Ferroptosis Synergistic Cancer Therapy in Combination with T1–T2 Dual-Mode Magnetic Resonance Imaging …

L Zhu, J Wang, X Tang, C Zhang, P Wang… - … Applied Materials & …, 2022 - ACS Publications
Excessive iron ions in cancer cells can catalyze H2O2 into highly toxic• OH and then
promote the generation of reactive oxygen species (ROS), inducing cancer ferroptosis …

Geriatric assessment in older adults with non-Hodgkin lymphoma: A Young International Society of Geriatric Oncology (YSIOG) review paper

OS Akhtar, LW Huang, M Tsang, P Torka… - Journal of geriatric …, 2022 - Elsevier
Non-Hodgkin lymphoma (NHL) is a disease of older adults, with a median age at diagnosis
of 67 years. Treatment in older adults with NHL is challenging. The aging process is …

[HTML][HTML] Exploring cost-effectiveness of the comprehensive geriatric assessment in geriatric oncology: a narrative review

S Zuccarino, F Monacelli, R Antognoli, A Nencioni… - Cancers, 2022 - mdpi.com
Simple Summary The Comprehensive Geriatric Assessment is a multidimensional and
multidisciplinary evaluation designed for elderly patients with the goal of structuring tailored …

Integrating geriatric assessment measures into National Cancer Institute clinical trials

A Magnuson, N Van der Walde, JM McKoy… - JNCI …, 2022 - academic.oup.com
To improve the care of older adults with cancer, the traditional approach to clinical trial
design needs to be reconsidered. Older adults are underrepresented in clinical trials with …

[HTML][HTML] Management of older adults with locally advanced head and neck cancer

DR Dickstein, EJ Lehrer, K Hsieh, A Hotca, BM Jones… - Cancers, 2022 - mdpi.com
Simple Summary Approximately one third of patients with head and neck cancer are older
adults. The number of older adults with head and neck cancer continues to rise especially as …

The evolution of geriatric oncology and geriatric assessment over the past decade

D Outlaw, M Abdallah, LA Gil-Jr, S Giri, T Hsu… - Seminars in radiation …, 2022 - Elsevier
Cancer is predominantly a disease of aging, and older adults represent the majority of
cancer diagnoses and deaths. Older adults with cancer differ significantly from younger …