The lymph node plays a critical role in mounting an adaptive immune response to infection,
clearance of foreign pathogens, and cancer immunosurveillance. Within this complex …

Vaccines protect against infections by eliciting both Ab and T cell responses. Because the
immunity wanes as protective epitopes get modified by accruing mutations, developing …

3.1 The immune system 3 3.2 Activation of CD8+ T cell by APCs 4 3.3 Ca2+-Calcineurin-
NFAT signalling in CD8+ T cells 5 3.4 CD8+ T-cell memory differentiation during acute …

In contrast to adults, neonates experience high morbidity and mortality from recurrent
intracellular infections. CD8+ T cells are responsible for killing intracellularly infected cells …

Malaria is caused by different Plasmodium species that can infect a variety of animals
including humans and rodents. The life cycle of these parasites is complex and includes a …

Advanced age is accompanied by a decline of immune functions, which may play a role in
low efficacy of vaccinations in elderly people. However, it is yet unclear at which level age …