[HTML][HTML] Pharmacological inhibition of HDAC6 improves muscle phenotypes in dystrophin-deficient mice by downregulating TGF-β via Smad3 acetylation

A Osseni, A Ravel-Chapuis, E Belotti, I Scionti… - Nature …, 2022 - nature.com
The absence of dystrophin in Duchenne muscular dystrophy disrupts the dystrophin-
associated glycoprotein complex resulting in skeletal muscle fiber fragility and atrophy …

[HTML][HTML] Membrane proteins increase with the repeated bout effect

SR Sidky, CP Ingalls, DA Lowe… - Medicine and science in …, 2022 - ncbi.nlm.nih.gov
PURPOSE: The ability of skeletal muscle to adapt to eccentric (ECC) contraction-induced
injury is known as the repeated bout effect (RBE). Despite the RBE being a well-established …

Mechanisms of weakness in Mdx muscle following in vivo eccentric contractions

CW Baumann, CP Ingalls, DA Lowe - Journal of muscle research and cell …, 2022 - Springer
Skeletal muscle of the dystrophin-deficient mdx mouse is hypersensitive to eccentric (ECC)
contraction-induced strength loss due to plasmalemmal electrical dysfunction. Despite …

[HTML][HTML] Studies on the manner of collateral regeneration from nerve stem to motor endplate

Z Qi, D Li, L Li, D Meng, J Deng, B Jin, X Gu… - Frontiers in …, 2022 - frontiersin.org
Despite recent evidence suggesting that nerve transfer techniques help improve clinical
outcomes, the underlying manner by which collateral-regenerated nerve enters skeletal …

Pharmacological inhibition of HDAC6 downregulates TGF-β via Smad2/3 acetylation and improves dystrophin-deficient muscles

A Osseni, A Ravel-Chapuis, I Scionti, YG Gangloff… - bioRxiv, 2022 - biorxiv.org
The absence of dystrophin in Duchenne muscular dystrophy (DMD) disrupts the dystrophin
dystroglycan glycoprotein complex (DGC) resulting in fibers fragility and atrophy, associated …

[PDF][PDF] ALEX DIAS ASSIS EFEITOS PROTETORES DA PREGABALINA NO SISTEMA NERVOSO PERIFÉRICO E SISTEMA MUSCULAR ESQUELÉTICO DE …

VFDATD PELO, AADAE ORIENTADO… - repositorio.unicamp.br
A distrofia muscular de Duchenne (DMD) é uma doença genética ligada ao cromossomo X
induzida por mutações no gene da distrofina. A distrofina anormal leva à degeneração das …

[图书][B] Decellularized Extracellular Matrix Hydrogel Therapy for the Prevention and Treatment of Pathological Alterations Following Birth Injuries

P Duran - 2022 - search.proquest.com
Pelvic floor disorders, which include pelvic organ prolapse, and urinary and fecal
incontinence, affect millions of women globally and represent a major public health concern …