16S rRNA methyltransferases as novel drug targets against tuberculosis
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis
(M. tb) whose natural history traces back to 70,000 years. TB remains a major global health …
(M. tb) whose natural history traces back to 70,000 years. TB remains a major global health …
Chemical biology and medicinal chemistry of RNA methyltransferases
TR Fischer, L Meidner, M Schwickert… - Nucleic Acids …, 2022 - academic.oup.com
RNA methyltransferases (MTases) are ubiquitous enzymes whose hitherto low profile in
medicinal chemistry, contrasts with the surging interest in RNA methylation, the arguably …
medicinal chemistry, contrasts with the surging interest in RNA methylation, the arguably …
Novel medicinal and synthetic chemistry strategies against antimicrobial resistance
E Rezaee, M Nazari, M Mosayebnia… - … Nanomaterials and Nano …, 2022 - Elsevier
As the entire world has been struggling with antimicrobial resistance during the past
decades, medicinal chemists have been doing their utmost to tackle this problem through …
decades, medicinal chemists have been doing their utmost to tackle this problem through …
[PDF][PDF] Development of DNMT2 inhibitors for the selective manipulation of the epitranscriptome
T Fischer - 2022 - openscience.ub.uni-mainz.de
The research discipline of epitranscriptomics dealing with ribonucleic acid (RNA)
modifications has gained increased popularity over the last decade. With the discovery of …
modifications has gained increased popularity over the last decade. With the discovery of …