Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …

Recent advances combining two-photon calcium imaging and two-photon optogenetics with
computer-generated holography now allow us to read and write the activity of large …

The combination of optogenetics and electrophysiological recording enables high-precision
bidirectional interactions between neural interfaces and neural circuits, which provides a …

Sleep disturbances are strongly associated with cardiovascular diseases. Baroreflex, a
basic cardiovascular regulation mechanism, is modulated by sleep-wake states. Here, we …

Deciphering the neural patterns underlying brain functions is essential to understanding
how neurons are organized into networks. This deciphering has been greatly facilitated by …

Dynamic interactions within and across brain areas underlie behavioral and cognitive
functions. To understand the basis of these processes, the activities of distributed local …

The neurobiological understanding of obsessive–compulsive disorder (OCD) includes
dysregulated frontostriatal circuitry and altered monoamine transmission. Repetitive …

Today's optical neuromodulation techniques are rapidly evolving, benefiting from advances
in photonics, genetics and materials science. In this review, we provide an up-to-date …

Rapid eye movement (REM) sleep disturbances are prevalent in various psychiatric
disorders. However, the neural circuits that regulate REM sleep remain poorly understood …

To understand the neural mechanisms of behavior, it is necessary to both monitor and
perturb the activity of ensembles of neurons with high specificity. While neural ensemble …