Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylchol...

Development of a highly efficient long-acting cocaine hydrolase entity to accelerate cocaine metabolism

F Zheng, Z Jin, J Deng, X Chen, X Zheng… - Bioconjugate …, 2022 - ACS Publications
It is particularly challenging to develop a truly effective pharmacotherapy for cocaine use
disorder (CUD) treatment. Accelerating cocaine metabolism via hydrolysis at cocaine …
被引用次数：10 相关文章 所有 4 个版本

Strategies for developing a recombinant butyrylcholinesterase medical countermeasure for Organophosphorus poisoning

JL Allard, KA Shields, TP Munro, LHL Lua - Chemico-Biological Interactions, 2022 - Elsevier
Organophosphorus nerve agents represent a serious chemical threat due to their ease of
production and scale of impact. The recent use of the nerve agent Novichok has re …
被引用次数：3 相关文章 所有 5 个版本
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Increased polypeptide production yields of butyrylcholinesterase polypeptides for therapeutic use

CG Zhan, F Zheng - US Patent 11,473,070, 2022 - Google Patents
US11473070B2 - Increased polypeptide production yields of butyrylcholinesterase
polypeptides for therapeutic use - Google Patents US11473070B2 - Increased polypeptide …
相关文章 所有 4 个版本