Ketones as strategic building blocks for the synthesis of natural product-inspired compounds
DJ Foley, H Waldmann - Chemical Society Reviews, 2022 - pubs.rsc.org
Natural product-inspired compound collections serve as excellent sources for the
identification of new bioactive compounds to treat disease. However, such compounds must …
identification of new bioactive compounds to treat disease. However, such compounds must …
[HTML][HTML] Rapid assembly of 1, 3-indanedione-based spirocyclic tetrahydroquinolines for inducing human lung cancer cell apoptosis
F Tan, L Chen, Y Yuan, X He, Y Su, S Cao, C Xie… - Green Synthesis and …, 2022 - Elsevier
The rapid collection of a library of biologically relevant molecules is essential in new drug
discovery. Here we show a variety of bioactive 1, 3-indanedione-based spirocyclic …
discovery. Here we show a variety of bioactive 1, 3-indanedione-based spirocyclic …
Selective C3-allylation and formal [3+ 2]-annulation of spiro-aziridine oxindoles: Synthesis of 5′-substituted spiro [pyrrolidine-3, 3′-oxindoles] and coerulescine
Brønsted acid-and/or Lewis acid-catalyzed selective C3-allylation and formal [3+ 2]-
annulation of spiro-aziridine oxindoles with allylsilanes have been demonstrated to deliver …
annulation of spiro-aziridine oxindoles with allylsilanes have been demonstrated to deliver …
Steroidal lactams: A review
M Ibrahim-Ouali, F Dumur - ARKIVOC-Online Journal of Organic …, 2022 - hal.science
Steroidal lactams are also a class of steroid derivatives that were synthesized and modified
to increase the biological activity of steroids. Their synthesis is a stimulating challenge to the …
to increase the biological activity of steroids. Their synthesis is a stimulating challenge to the …