Decreased number and function of beta cells are a key aspect of diabetes mellitus
(diabetes), a disease that remains an onerous global health problem. Means of restoring …

Diabetes is a complex metabolic disorder of carbohydrate metabolism, characterized by
high blood glucose levels either due to an absolute deficiency of insulin secretion or an …

The pancreatic β-cells are essential for regulating glucose homeostasis through the
coordinated release of the insulin hormone. Dysfunction of the highly specialized β-cells …

Studies in animal diabetic models have demonstrated the possibility of islet regeneration
through treatment with natural extracts, such as Allium sativum (garlic). This study aimed to …

Up to 6% of diabetes has a monogenic cause including mutations in the insulin gene, and
patients are candidates for a gene therapy. Using a mouse model of permanent neonatal …