The left atrium is a dynamic chamber with peculiar characteristics. Stressors and disease
mechanisms may deeply modify its structure and function, leading to left atrial remodelling …

Recent preclinical and observational cohort studies have implicated imbalances in gut
microbiota composition as a contributor to atrial fibrillation (AF). The gut microbiota is a …

Cardiac electrophysiology is a complex system established by a plethora of inward and
outward ion currents in cardiomyocytes generating and conducting electrical signals in the …

Atrial fibrillation (AF) remains the most common arrhythmia seen clinically. The incidence of
AF is increasing due to the aging population. AF is associated with a significant increase in …

Background Little is known about genome-wide changes in the atrial transcriptome as a
cause or consequence of atrial fibrillation (AF), and the effect of its common and clinically …

Backgrounds Non-valvular atrial fibrillation (AF) is the most common type of cardiac
arrhythmia. AF is caused by electrophysiological abnormalities and alteration of atrial …

Chronic kidney disease (CKD) shows a high prevalence and is characterized by progressive
and irreversible loss of renal function. It is also associated with a high risk of cardiovascular …

Background Atrial fibrillation (AF) is the most common age-related cardiac arrhythmia. The
etiology underlying AF is still largely unknown. At the intersection of the innate immune …

A hallmark of atrial fibrillation is an excess of spontaneous calcium release events, which
can be mimicked by β1-or β2-adrenergic stimulation. Because β1-adrenergic receptor …

Background Inflammation plays a key role in the initiation and progression of atrial fibrillation
(AF). Lymphocyte‐to‐monocyte ratio (LMR) has been proved to be a reliable predictor of …