During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …

Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

Bispecific antibodies (BsAbs) are emerging as an important novel class of
immunotherapeutic agents for the treatment of multiple myeloma (MM), and are set to be …

Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Background Rezafungin is a next-generation, once-a-week echinocandin in development
for the treatment of candidaemia and invasive candidiasis and for the prevention of invasive …

Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …

Summary Background The European Confederation of Medical Mycology (ECMM) collected
data on epidemiology, risk factors, treatment, and outcomes of patients with culture-proven …

Importance Bloodstream infections (BSIs) are a major public health problem associated with
high morbidity. Little evidence exists regarding the epidemiology of BSIs and the use of …

Background Fosmanogepix is a first-in-class antifungal targeting the fungal enzyme Gwt1,
with broad-spectrum activity against yeasts and moulds, including multidrug-resistant fungi …