Hepatitis C virus (HCV), a global malady, causes acute and chronic hepatitis leading to
permanent liver damage, hepatocellular carcinoma, and death. Modern anti‐HCV therapies …

Since its outbreak in December 2019, the COVID-19 pandemic has caused the death of
more than 6.5 million people around the world. The high transmissibility of its causative …

The synthesis of dialkyl-substituted cyclopropanes is an important challenge in synthesis
with applications in drug discovery and agrochemistry. Herein, we report on the synthesis of …

Direct-acting antiviral agents (DAAs) provide efficacious therapeutic treatments for chronic
Hepatitis C virus (HCV) infection. However, emergence of drug resistance mutations (DRMs) …

Hepatitis C virus (HCV) is a global public health concern with significant impacts. It primarily
spreads through blood-to-blood contact, such as sharing needles among drug users. Given …

Viral proteases play a crucial role in viral infection and are regarded as promising targets for
antiviral drug development. Consequently, biosensing methods that target viral proteases …

Macrocyclic compounds, characterized by cyclic structures, often originate from either
modified forms of unicyclic canonical molecules or natural products. Within the field of …

A palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of alkynes via C
(sp3)–H activation has been developed for the synthesis of cyclopropane-fused γ-lactams …

Viruses have the ability to modulate the cellular machinery of their host to ensure their
survival. While humans encounter numerous viruses daily, only a select few can lead to …

Hepatitis C infection is a leading etiology of hepatic dysfunction and a major indication for
liver transplantation due to the development of fibrosis, cirrhosis, and hepatocellular …