Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …

For several decades, most lung cancer investigations have focused on the search for
mutations in candidate genes; however, in the last decade, due to the fact that most of the …

Particulate matter (PM), one of the most serious air contaminants, could easily pass through
the airway and deposit at the deep alveoli. Thus, it might trigger respiratory diseases like …

The pathogenesis of lung cancer (LC) is a multifaceted process that is influenced by a
variety of factors. Alongside genetic mutations and environmental influences, there is …

Up to 18% of cancer-related deaths worldwide are attributed to lung tumor and global
burden of this type of cancer is ascending. Different factors are responsible for development …

Abstract Pyruvate dehydrogenase kinase 1 (PDK1) is a widely known glycolytic enzyme,
and some evidence showed that PDK1 promoted breast cancer by multiple approaches …

Epithelial to mesenchymal transition (EMT) represents a phenotypic change that occurs in
epithelial tumors that is required for cancer cells to acquire metastatic potential. This …