Diagnosis and management of endometriosis

C Allaire, MA Bedaiwy, PJ Yong - Cmaj, 2023 - Can Med Assoc
• Endometriosis is a common disorder that can cause pelvic pain and infertility, may involve
multiple organ systems and can adversely affect quality of life.• The cause of endometriosis …

Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities

IM McGrath, GW Montgomery… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Endometriosis remains a poorly understood disease, despite its high
prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of …

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

N Rahmioglu, S Mortlock, M Ghiasi, PL Møller… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

The bidirectional relationship between endometriosis and microbiome

C Uzuner, J Mak, F El-Assaad… - Frontiers in Endocrinology, 2023 - frontiersin.org
Endometriosis has been described by many different theories of pathogenesis over the
years. It is now also appreciated to be a state of chronic inflammation, and the role of …

New concepts on the etiology of endometriosis

FL Cousins, BD McKinnon, S Mortlock… - Journal of Obstetrics …, 2023 - Wiley Online Library
Endometriosis is a serious, chronic disorder where endometrial tissue grows outside the
uterus, causing severe pelvic pain and infertility. It affects 11% of women. Endometriosis is a …

Genomic characterisation of the overlap of endometriosis with 76 comorbidities identifies pleiotropic and causal mechanisms underlying disease risk

IM McGrath… - Human Genetics, 2023 - Springer
Comorbid conditions can be driven by underlying pleiotropic and causal mechanisms that
can provide insights into shared molecular and biological processes contributing to disease …

Association of endometriosis with cardiovascular disease: Genetic aspects

VM Vazgiourakis, MI Zervou… - International …, 2023 - spandidos-publications.com
Cardiovascular disease (CVD) comprises a broad spectrum of pathological conditions that
affect the heart or blood vessels, including sequelae that arise from damaged vasculature in …

Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone

IM McGrath… - BMC medicine, 2023 - Springer
Background Endometriosis affects 1 in 9 women, yet it is poorly understood with long
diagnostic delays, invasive diagnoses, and poor treatment outcomes. Characterised by the …

[HTML][HTML] Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations

LC Giudice, TT Oskotsky, S Falako… - The FASEB …, 2023 - ncbi.nlm.nih.gov
Endometriosis is a common estrogen‐dependent disorder wherein uterine lining tissue
(endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic …

[HTML][HTML] Генетические детерминанты уровня половых гормонов у больных эндометриозом

ИО Головченко - Научные результаты биомедицинских …, 2023 - cyberleninka.ru
Актуальность: Эндометриоз-это хроническое гормонозависимое воспалительное
заболевание, определяемое наличием очагов эндометриальной ткани вне полости …