A 360 view of the inflammasome: Mechanisms of activation, cell death, and diseases
Inflammasomes are critical sentinels of the innate immune system that respond to threats to
the host through recognition of distinct molecules, known as pathogen-or damage …
the host through recognition of distinct molecules, known as pathogen-or damage …
[HTML][HTML] Innate immune evasion strategies of SARS-CoV-2
JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
associated with substantial global morbidity and mortality. Despite a tropism that is largely …
[HTML][HTML] COVID-19 and cellular senescence
CA Schmitt, T Tchkonia, LJ Niedernhofer… - Nature Reviews …, 2023 - nature.com
The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …
Autoimmune and autoinflammatory connective tissue disorders following COVID-19
SH Lim, HJ Ju, JH Han, JH Lee, WS Lee… - JAMA network …, 2023 - jamanetwork.com
Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19
have been reported. However, their incidences and risks have rarely been quantified …
have been reported. However, their incidences and risks have rarely been quantified …
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review
L Ghosn, R Assi, T Evrenoglou… - Cochrane database …, 2023 - cochranelibrary.com
Background It has been reported that people with COVID‐19 and pre‐existing
autoantibodies against type I interferons are likely to develop an inflammatory cytokine storm …
autoantibodies against type I interferons are likely to develop an inflammatory cytokine storm …
[HTML][HTML] Cytokine storm syndrome
Cytokine storm syndrome (CSS), which is frequently fatal, has garnered increased attention
with the ongoing coronavirus pandemic. A variety of hyperinflammatory conditions …
with the ongoing coronavirus pandemic. A variety of hyperinflammatory conditions …
[HTML][HTML] A review of cytokine-based pathophysiology of Long COVID symptoms
RN Low, RJ Low, A Akrami - Frontiers in Medicine, 2023 - frontiersin.org
The Long COVID/Post Acute Sequelae of COVID-19 (PASC) group includes patients with
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …
[HTML][HTML] Impact of COVID-19 on cardiovascular disease
Coronavirus disease 2019 (COVID-19) is a viral infection with the novel severe acute
respiratory distress syndrome corona virus 2 (SARS-CoV-2). Until now, more than 670 …
respiratory distress syndrome corona virus 2 (SARS-CoV-2). Until now, more than 670 …
[HTML][HTML] An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2
Elevated levels of cytokines IL-1β and IL-6 are associated with severe COVID-19.
Investigating the underlying mechanisms, we find that while primary human airway epithelia …
Investigating the underlying mechanisms, we find that while primary human airway epithelia …
Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis
MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …