[HTML][HTML] Reduction in the activity of VTA/SNc dopaminergic neurons underlies aging-related decline in novelty seeking
Q Shan, Y Tian, H Chen, X Lin, Y Tian - Communications Biology, 2023 - nature.com
Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore
and exploit environments to improve survival, and is also positively associated with …
and exploit environments to improve survival, and is also positively associated with …
[HTML][HTML] Multiple neuron clusters on Micro-Electrode Arrays as an in vitro model of brain network
Understanding the brain functioning is essential for governing brain processes with the aim
of managing pathological network dysfunctions. Due to the morphological and biochemical …
of managing pathological network dysfunctions. Due to the morphological and biochemical …
[HTML][HTML] Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons
Dopa-responsive dystonia (DRD) and Parkinson's disease (PD) are movement disorders
caused by the dysfunction of nigrostriatal dopaminergic neurons. Identifying druggable …
caused by the dysfunction of nigrostriatal dopaminergic neurons. Identifying druggable …
[HTML][HTML] A Network-Level Stochastic Model for Pacemaker GABAergic Neurons in Substantia Nigra Pars Reticulata
K Guimarães, A Duarte - Mathematics, 2023 - mdpi.com
In this paper we present computational simulations of a mathematical model describing the
time evolution of membrane potentials in a GABAergic neural network. This model, with …
time evolution of membrane potentials in a GABAergic neural network. This model, with …
Detecting rhythmic spiking through the power spectra of point process model residuals
Oscillations figure prominently in models of brain function and dysfunction. It would be
informative to analyze oscillations at the level of individual neurons, by estimating the power …
informative to analyze oscillations at the level of individual neurons, by estimating the power …