Role of basic fibroblast growth factor in cancer: biological activity, targeted therapies, and prognostic value

A Ardizzone, V Bova, G Casili, A Repici, M Lanza… - Cells, 2023 - mdpi.com
Cancer is the leading cause of death worldwide; thus, it is necessary to find successful
strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic …

[PDF][PDF] Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin

WW Liang, RJH Lu, RG Jayasinghe, SM Foltz… - Cancer cell, 2023 - cell.com
DNA methylation plays a critical role in establishing and maintaining cellular identity.
However, it is frequently dysregulated during tumor development and is closely intertwined …

miRNA-381-3p functions as a tumor suppressor to inhibit gastric cancer by targeting fibroblast growth factor receptor-2

X Gao, H Liu, Q Wu, R Wang, M Huang… - Cancer Biotherapy & …, 2023 - liebertpub.com
Objectives: MicroRNAs possess essential effects on gastric cancer (GC), whereas the
underlying mechanisms have not been fully uncovered. The present work focused on …

Oncogenic signaling pathways and hallmarks of cancer in Korean patients with acral melanoma

SR Moon, HJ Kim, Y Lee, YJ Lee, S Jung… - Computers in Biology …, 2023 - Elsevier
Acral melanoma (AM), a rare subtype of cutaneous melanoma, shows higher incidence in
Asians, including Koreans, than in Caucasians. However, the genetic modification …

Leptinin yara iyileşmesi üzerine in vitro etkisinin büyüme faktörleri üzerinden incelenmesi

MÖ Önal, H Elbe, G Yiğittürk, V Yaşar… - Muğla Sıtkı Koçman …, 2023 - dergipark.org.tr
Yara iyileşmesi; epitelyal, endotelyal, mezenkimal ve inflamatuvar hücrelerin biraraya gelip,
normal işlevlerini belirli bir sıra ve düzen içerisinde yerine getirmeleriyle karakterizedir …