SGLT2 (sodium-glucose cotransporter 2) inhibitors interfere with the reabsorption of glucose
and sodium in the early proximal renal tubule, but the magnitude and duration of any …

Aims To evaluate whether the addition of hydrochlorothiazide (HCTZ) to intravenous
furosemide is a safe and effective strategy for improving diuretic response in acute heart …

Measurement of natriuresis has been suggested as a reliable, easily obtainable biomarker
for assessment of the response to diuretic treatment in patients with acute heart failure …

Aims Acetazolamide inhibits proximal tubular sodium and bicarbonate re-absorption and
improved decongestive response in acute heart failure in the ADVOR trial. It is unknown …

Background Acetazolamide facilitates decongestion in acute decompensated heart failure
(ADHF). Objectives This study sought to investigate the effect of acetazolamide on …

Aims Acetazolamide, an inhibitor of proximal tubular sodium reabsorption, leads to more
effective decongestion in acute heart failure (AHF). It is unknown whether acetazolamide …

Despite worsening heart failure (HF) being extremely common, expensive, and associated
with substantial risk of death, there remain no dedicated clinical practice guidelines for the …

Abstract Background and Aims In the ADVOR trial, acetazolamide improved decongestion in
acute decompensated heart failure (ADHF). Whether the beneficial effects of acetazolamide …

Aims In patients with acute heart failure (AHF), the addition of hydrochlorothiazide (HCTZ) to
furosemide improved diuretic response in the CLOROTIC trial. This work aimed to evaluate if …

Background: Acetazolamide inhibits proximal tubular sodium reabsorption and improved
decongestion in the ADVOR (Acetazolamide in Decompensated Heart Failure with Volume …