The evolving biology of cross-presentation

RA Ohara, KM Murphy - Seminars in immunology, 2023 - Elsevier
Cross-priming was first recognized in the context of in vivo cytotoxic T lymphocyte (CTL)
responses generated against minor histocompatibility antigens induced by immunization …

[HTML][HTML] Tolerogenic dendritic cells in type 1 diabetes: no longer a concept

N Giannoukakis - Frontiers in Immunology, 2023 - frontiersin.org
Tolerogenic dendritic cells (tDC) arrest the progression of autoimmune-driven dysglycemia
into clinical, insulin-requiring type 1 diabetes (T1D) and preserve a critical mass of β cells …

[HTML][HTML] Advances and key focus areas in gastric cancer immunotherapy: A comprehensive scientometric and clinical trial review (1999-2023)

YN Li, B Xie, Y Zhang, MH He, Y Xing… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Gastric cancer (GC) is the sixth most common cancer and third leading
cause of cancer-related deaths worldwide. Current treatments mainly rely on surgery-and …

Optimizing the generation of mature bone marrow-derived dendritic cells in vitro: a factorial study design

N Alotaibi, A Aldahlawi, K Zaher, F Basingab… - Journal of Genetic …, 2023 - Elsevier
Background Factorial design is a simple, yet elegant method to investigate the effect of
multiple factors and their interaction on a specific response simultaneously. Hence, this type …

[HTML][HTML] Characterization of CAR T Cells Manufactured Using Genetically Engineered Artificial Antigen Presenting Cells

A Sayadmanesh, M Azadbakht, K Yari… - Cell Journal …, 2023 - ncbi.nlm.nih.gov
Objective: Chimeric antigen receptor (CAR) T cell therapy has recently emerged as a
promising approach for the treatment of different types of cancer. Improving CAR T cell …

Vaccination of autologous dendritic cells induces early protection against the Foot-and-mouth disease virus in pigs by enhancing T-cell immunity

S Mu, L Chen, S Li, H Dong, Y Zhang, S Yin, Y Tian… - 2023 - researchsquare.com
Foot-and-mouth disease virus (FMDV) remains a challenge for cloven-hooved animals. The
currently-licensed FMDV vaccines induce neutralizing antibody (NAb)-mediated protection …