The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

Background Genetic factors play an important role in prostate cancer (PCa) susceptibility.
Objective To discover common genetic variants contributing to the risk of PCa in men of …

Prostate cancer (PrCa) is the second most common cancer worldwide in males. While
strongly warranted, the prediction of mortality risk due to PrCa, especially before its …

To date, single-nucleotide polymorphisms (SNPs) have been the most intensively
investigated class of polymorphisms in genome wide associations studies (GWAS) …

Simple Summary The human genome produces various types of RNA molecules. A
significant portion of these are long non-coding RNAs (lncRNAs) exceeding 200 nts without …

Prostate carcinoma is a malignant situation that arises from genomic alterations in the
prostate, leading to changes in tumorigenesis. The NF-κB pathway modulates various …

Cancer is increasingly recognized as an extraordinarily heterogeneous disease featuring an
intricate mutational landscape and vast intra-and intertumor variability on both genetic and …

Prostate cancer (PCa) brings huge public health burden in men. A growing number of
conventional observational studies report associations of multiple circulating proteins with …

Abstract Polyglutamine binding protein 5 (PQBP5), also called nucleolar protein 10
(NOL10), binds to polyglutamine tract sequences and is expressed in the nucleolus. Using …

Background Aberrant somatic genomic alteration including copy number amplification is a
hallmark of cancer genomes. We previously profiled genomic landscapes of prostate cancer …