Personalizing direct oral anticoagulant therapy for a diverse population: role of race, kidney function, drug interactions, and pharmacogenetics

LE Thompson, BH Davis, R Narayan… - Clinical …, 2023 - Wiley Online Library
Oral anticoagulants (OACs) are commonly used to reduce the risk of venous
thromboembolism and the risk of stroke in patients with atrial fibrillation. Endorsed by the …

Severe bleeding risk of direct oral anticoagulants versus vitamin K antagonists for stroke prevention and treatment in patients with atrial fibrillation: a systematic review …

W Xu, M Lv, S Wu, S Jiang, Z Zeng, Z Fang… - … Drugs and Therapy, 2023 - Springer
Purpose We aimed to determine the safety of direct oral anticoagulants (DOACs) for stroke
prevention and treatment in patients with atrial fibrillation (AF). Methods A systematic search …

Effect of edoxaban compared with other oral anticoagulants for stroke prevention in patients with atrial fibrillation: A meta-analysis

B Zhang, W Cheng, W Kaisaier, Z Gu, W Zhu, Q Jiang - Heliyon, 2023 - cell.com
Background and aim Current observational studies have compared the effectiveness and
safety of edoxaban with other oral anticoagulants in patients with AF, but the results are still …

Clinical Outcomes in Patients With Atrial Fibrillation Treated With Non–Vitamin K Oral Anticoagulants Across Varying Body Mass Index

A Fritz Hansson, K Jensevik Eriksson… - Journal of the …, 2023 - Am Heart Assoc
Background There are conflicting data on outcomes in patients with atrial fibrillation treated
with non–vitamin K oral anticoagulants across varying body mass index (BMI). We …

Integrated analysis of clinical and genetic factors on the interindividual variation of warfarin anticoagulation efficacy in clinical practice

B Sun, S Ma, F Xiao, J Luo, M Liu, W Liu… - BMC Cardiovascular …, 2023 - Springer
Aim The anticoagulation effect of warfarin is usually evaluated by percentage of time in
therapeutic range (PTTR), which is negatively correlated with the risk of warfarin adverse …

Safety and efficacy of oral anticoagulants in extreme weights

J Chin-Hon, L Davenport, J Huang, M Akerman… - Thrombosis …, 2023 - Elsevier
Abstract Background The 2021 International Society on Thrombosis and
Haemostasis'(ISTH) recommends standard doses of apixaban and rivaroxaban regardless …

[HTML][HTML] Better Survival in Morbidly Obese Patients with Atrial Fibrillation Treated with Non-vitamin K-dependent Oral Anticoagulants

MA Albabtain, Z Alanazi, N Al Mutairi… - Journal of the Saudi …, 2023 - ncbi.nlm.nih.gov
Background The efficacy and safety of non-vitamin K-dependent anticoagulants (NOAC) are
not well investigated in the obese population, and fixed dosing could lead to under …

[PDF][PDF] Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options

M Kalla, AP Holmes, C O'Shea, D Pavlovic - 2023 - core.ac.uk
Atrial fibrillation (AF) is the most common cardiac arrhythmia. AF increases the risk of stroke,
heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both …

Non-Vitamin K Antagonist Oral Anticoagulants in Differentiated Approach to the Use in Cardiological Practice: Literature Review

LA Vozniuk, OV Dzekan, SO Siromakha - Ukrainian Journal of …, 2023 - cvs.org.ua
Non-vitamin K antagonist oral anticoagulants (novel oral anticoagulants, NOACs) are
important pharmaceuticals for prevention of stroke and systemic embolism in non-valvular …

[PDF][PDF] Atriyal Fibrilasyon ve İlişkili Risk Gruplarında Direkt Oral Antikoagülanların Kullanımı: Geleneksel Derleme.

YE AYHAN, D ÜNDER, EE İLERLER, İ MİDİ… - Journal of Literature …, 2023 - academia.edu
Atriyal fibrilasyonu (AF) olan hastalarda tromboembolik olay riskini azaltmak için oral
antikoagülanların rolü çok önemlidir. Bu amaçla, yaygın olarak kullanılan antikoagülan ilaç …