Anti-inflammatory effects of 2nd generation antipsychotics in patients with schizophrenia: A systematic review and meta-analysis

SR Patlola, G Donohoe, DP McKernan - Journal of Psychiatric Research, 2023 - Elsevier
Background Schizophrenia is a major psychiatric disorder with unknown aetiology. Recent
evidence suggests a potential role for cytokines in its pathophysiology and that antipsychotic …

Novel pharmacotherapy targeting the positive symptoms of schizophrenia

E Capuzzi, A Caldiroli, C Quitadamo… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The severity of positive symptoms in schizophrenia is associated with poor
prognosis. About one-third of schizophrenia patients partially respond to treatment with …

Altered cytokine levels in the cerebrospinal fluid of adult patients with autism spectrum disorder

K Runge, BL Fiebich, H Kuzior, J Rausch… - Journal of Psychiatric …, 2023 - Elsevier
Background Despite intensive research, the etiological causes of autism spectrum disorder
(ASD) remain elusive. Immunological mechanisms have recently been studied more …

High rate of discontinuation during long-acting injectable antipsychotic treatment in patients with psychotic disorders

AM Auxilia, M Buoli, A Caldiroli, GS Carnevali… - Biomedicines, 2023 - mdpi.com
Treatment discontinuation is a major challenge in routine clinical settings. Despite poor
adherence to antipsychotic medication, long acting injectable (LAI) formulations are an …

Longitudinal study of inflammation and relapse in schizophrenia

BJ Miller, H Lemos, NR Schooler, DC Goff… - Schizophrenia …, 2023 - Elsevier
Introduction The clinical course of schizophrenia is often characterized by recurrent
relapses. Blood inflammatory markers are altered in acute psychosis, and may be state …

[HTML][HTML] The deficit subtype of schizophrenia is associated with a pro-inflammatory phenotype but not with altered levels of zonulin: Findings from a case-control study

A Cyran, E Pawlak, P Piotrowski, T Bielawski… - …, 2023 - Elsevier
There is evidence that subclinical inflammation and increased gut permeability might be
involved in the pathophysiology of schizophrenia. Less is known about these phenomena in …

Neutrophil gelatinase-associated lipocalin (NGAL) and tumor necrosis factor-α (TNF-α) levels in patients with schizophrenia

A Gül Çakıl, H Kaya, A Sakallı Nural, IB Çakmak… - …, 2023 - Springer
Rationale Although the immune system is thought to contribute to the etiology of
schizophrenia, the mechanism has not been elucidated. Clarifying the relationship between …

Changes in inflammatory markers in clinical high risk of developing psychosis

TH Zhang, JH Zeng, YY Wei, JY Ye, XC Tang… - …, 2023 - karger.com
Introduction: Immune alterations are associated with the progression of psychosis. However,
there are few studies designed to longitudinally measure inflammatory biomarkers during …

Correlation between elevated serum interleukin-1β, interleukin-16 levels and psychiatric symptoms in patients with schizophrenia at different stages

X Cheng, Y Xie, A Wang, C Zhu, F Yan, W Pei, X Zhang - BMC psychiatry, 2023 - Springer
Background There is increasing evidence that immune dysfunction plays an important role
in the pathogenesis of schizophrenia. Meso Scale Discovery (MSD) is bioanalytical method …

Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of mental health symptoms in patients with post-acute sequelae of …

AL Cheng, J Anderson, N Didehbani… - PM & R: the journal …, 2023 - pubmed.ncbi.nlm.nih.gov
Multi-disciplinary collaborative consensus guidance statement on the assessment and
treatment of mental health symptoms in patients with post-acute sequelae of SARS-CoV-2 …