Advances in mitophagy and mitochondrial apoptosis pathway-related drugs in glioblastoma treatment
W Li, X Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
Glioblastoma (GBM) is the most common malignant tumor of the central nervous system
(CNS). It is a leading cause of death among patients with intracranial malignant tumors …
(CNS). It is a leading cause of death among patients with intracranial malignant tumors …
Electro-conductive chitosan/graphene bio-nanocomposite scaffold for tissue engineering of the central nervous system
Degenerative central nervous system (CNS) disorders and traumatic brain injuries are
common nowadays. These may induce the loss of neuronal cells and delicate connections …
common nowadays. These may induce the loss of neuronal cells and delicate connections …
Gallate moiety of catechin Is essential for inhibiting CCL2 chemokine-mediated monocyte recruitment
Leukocyte recruitment witnesses an orchestrated complex formation between the
chemokines and their molecular partners. CCL2 chemokine that regulates monocyte …
chemokines and their molecular partners. CCL2 chemokine that regulates monocyte …
Pterostilbene-Isothiocyanate Inhibits Proliferation of Human MG-63 Osteosarcoma Cells via Abrogating β-Catenin/TCF-4 Interaction─ A Mechanistic Insight
Osteosarcoma, a highly metastasizing bone neoplasm, is a leading cause of death and
disability in children and adolescents worldwide. Osteosarcoma is only suboptimally …
disability in children and adolescents worldwide. Osteosarcoma is only suboptimally …
The role of TMEM26 in disrupting tight junctions and activating NF-κB signaling to promote epithelial-mesenchymal transition in esophageal squamous cell carcinoma
G Han, S Zhou, J Shen, Y Yang, X Bian, Y Li, R Ling… - Clinics, 2023 - SciELO Brasil
Objectives Metastasis is one of the biggest challenges in the management of Esophageal
Squamous Cell Carcinoma (ESCC), of which molecular mechanisms remain elusive. The …
Squamous Cell Carcinoma (ESCC), of which molecular mechanisms remain elusive. The …
Synthesis, In Vitro, and In Vivo Investigations of Pterostilbene-Tethered Analogues as Anti-Breast Cancer Candidates
G Li, J Li, W Wang, X Feng, X Yu, S Yuan… - International Journal of …, 2023 - mdpi.com
Pterostilbene has been found to be an active scaffold with anti-breast cancer (BC) action. In
this study, fourteen pterostilbene-tethered analogues (2A–2N) were prepared and screened …
this study, fourteen pterostilbene-tethered analogues (2A–2N) were prepared and screened …
Pterostilbene–isothiocyanate reduces miR-21 level by impeding Dicer-mediated processing of pre-miR-21 in 5-fluorouracil and tamoxifen-resistant human breast …
Converging evidences identifies that microRNA-21 (miR-21) is responsible for drug
resistance in breast cancer. This study aims to evaluate the miR-21-modulatory potential of a …
resistance in breast cancer. This study aims to evaluate the miR-21-modulatory potential of a …