Autophagy is the process by which cells degrade and recycle proteins and organelles to
maintain intracellular homeostasis. Generally, autophagy plays a protective role in cells, but …

With the aging of global population, the incidence of nonalcoholic fatty liver disease
(NAFLD) has surged in recent decades. NAFLD is a multifactorial disease that follows a …

Alzheimer's disease is a prevalent form of dementia among elderly individuals and is
characterized by irreversible neurodegeneration. Despite extensive research, the exact …

The pathogenesis of hepatocellular carcinoma (HCC) is a multifactorial process that has not
yet been fully investigated. Autophagy and apoptosis are two important cellular pathways …

Sequestosome 1 (SQSTM1/p62; hereafter p62) is an autophagy receptor protein for
selective autophagy primarily due to its direct interaction with the microtubule light chain 3 …

Abstract Background Ufm1-specific ligase 1 (Ufl1) and Ufm1-binding protein 1 (Ufbp1), as
putative targets of ubiquitin-fold modifier 1 (Ufm1), have been implicated in several …

Aim To evaluate the effect of lycopene on carbon tetrachloride (CCl 4)-induced hepatic
fibrosis and elucidate the underlying mechanism. Methods Male rats were randomly …

Autophagy is a highly conserved process in which cytosolic contents are degraded by the
lysosome, which plays an important role in energy and nutrient balance, and protein or …

Background Radiation‐induced skin injury, which may progress to fibrosis, is a severe side
effect of radiotherapy in patients with cancer. However, currently, there is a lack of preventive …

To explore the molecular mechanism of autologous blood transfusion promoting autophagy
of hepatocellular carcinoma (HCC) cells and inhibiting the HCC progression through HIF‐1α …