Does repeated influenza vaccination attenuate effectiveness? A systematic review and meta-analysis

E Jones-Gray, EJ Robinson, AJ Kucharski… - The Lancet …, 2023 - thelancet.com
Background Influenza vaccines require annual readministration; however, several reports
have suggested that repeated vaccination might attenuate the vaccine's effectiveness. We …

Advances in adjuvanted influenza vaccines

S Shichinohe, T Watanabe - Vaccines, 2023 - mdpi.com
The numerous influenza infections that occur every year present a major public health
problem. Influenza vaccines are important for the prevention of the disease; however, their …

Vaccine effectiveness against influenza A (H3N2)–associated hospitalized illness: United States, 2022

MW Tenforde, MM Patel, NM Lewis… - Clinical Infectious …, 2023 - academic.oup.com
Background The COVID-19 pandemic was associated with historically low influenza
circulation during the 2020–2021 season, followed by an increase in influenza circulation …

[HTML][HTML] Intraseasonal waning immunity of seasonal influenza vaccine–A systematic review and meta-analysis

P Doyon-Plourde, J Przepiorkowski, K Young, L Zhao… - Vaccine, 2023 - Elsevier
Background Recently, studies have suggested that influenza antibody titers decline with
time since vaccination. Duration of vaccine protection is an important factor to determine the …

The negative effect of preexisting immunity on influenza vaccine responses transcends the impact of vaccine formulation type and vaccination history

SA Moritzky, KA Richards, MA Glover… - The Journal of …, 2023 - academic.oup.com
The most effective measure to induce protection from influenza is vaccination. Thus, yearly
vaccination is recommended, which, together with infections, establishes diverse repertoires …

Systematic review of influenza vaccine effectiveness against laboratory-confirmed influenza among older adults living in aged care facilities

A Moa, M Kunasekaran, Z Akhtar… - Human vaccines & …, 2023 - Taylor & Francis
We estimated the effectiveness of influenza vaccines in preventing laboratory-confirmed
influenza among older adults in aged care. Electronic database searches were conducted …

Heterologous Prime-Boost Vaccination with Inactivated Influenza Viruses Induces More Effective Cross-Protection than Homologous Repeat Vaccination

N Bhatnagar, KH Kim, J Subbiah… - Vaccines, 2023 - mdpi.com
With concerns about the efficacy of repeat annual influenza vaccination, it is important to
better understand the impact of priming vaccine immunity and develop an effective …

Repeated influenza vaccination induces similar immune protection as first‐time vaccination but with differing immune responses

B Ye, L Shu, Y Pang, Y Guo, Y Guo… - Influenza and Other …, 2023 - Wiley Online Library
Background Recent seasonal epidemics of influenza have been caused by human influenza
A viruses of the H1N1 and H3N2 subtypes and influenza B viruses. Annual vaccination is …

A Multiseason Randomized Controlled Trial of Advax-Adjuvanted Seasonal Influenza Vaccine in Participants With Chronic Disease or Older Age

D Sajkov, R Woodman, Y Honda-Okubo… - The Journal of …, 2023 - academic.oup.com
Background The aim of the current study was to determine the safety and immunogenicity of
trivalent inactivated influenza vaccine (TIV) alone or formulated with Advax delta inulin …

Influenza vaccine effectiveness in preventing laboratory-confirmed influenza cases and hospitalizations in Navarre, Spain, 2022–2023

I Martínez-Baz, M Fernández-Huerta, A Navascués… - Vaccines, 2023 - mdpi.com
We estimated influenza vaccine effectiveness (IVE) in preventing outpatient and hospitalized
cases in the 2022–2023 season. A test-negative design included a representative sample of …