[HTML][HTML] Primary adrenal insufficiency induced by immune checkpoint inhibitors: Biological, clinical, and radiological aspects

S Martella, M Lucas, M Porcu, L Perra, N Denaro… - Seminars in …, 2023 - Elsevier
Immune checkpoint inhibitors (ICI) have become a cornerstone in medical oncology,
continually evolving therapeutic strategies and applications. These monoclonal antibodies …

The management and metabolic characterization: hyperthyroidism and hypothyroidism

Y Wang, YP Sun, B Yang, Q Wang, H Kuang - Neuropeptides, 2023 - Elsevier
Hyperthyroidism and hypothyroidism are common diseases resulting from thyroid
dysfunction, and are simple to diagnose and treat. The traditional treatment for …

Virus‐Like Nanotherapeutic for Spatiotemporally Enhancing Antigen Presentation and Cross‐Presentation toward Potential Personalized Immunotherapy

X Li, P Yuan, H Yang, X Zong, C Yang… - Advanced …, 2023 - Wiley Online Library
One of the major causes of immunotherapy resistance is the loss of major histocompatibility
complex class I (MHC‐I) molecules in tumor cells or the downregulation of the class I …

A review of immune checkpoint blockade for the general surgeon

XL Baldwin, PM Spanheimer… - Journal of Surgical …, 2023 - Elsevier
The immune system is a complex and interconnected system that has evolved to protect its
host from foreign pathogens. CD8+ T cells are a type of immune cell that can be directly …

[HTML][HTML] Imaging for assessment of cancer treatment response to immune checkpoint inhibitors can be complementary in identifying hypophysitis

A Galligan, A Iravani, A Lasocki, R Wallace… - Frontiers in …, 2023 - frontiersin.org
Introduction Hypophysitis is reported in 8.5%–14% of patients receiving combination
immune checkpoint inhibition (cICI) but can be a diagnostic challenge. This study aimed to …

[HTML][HTML] Incidence and Timing of Immune-Related Adverse Events in Immune-Checkpoint Inhibitor-Treated Patients: A Retrospective Observational Study

K Masaki, M Miyazaki, H Kakimoto, Y Fukiage… - Journal of Clinical …, 2023 - mdpi.com
Background: Immune-checkpoint inhibitors (ICIs) are effective against various cancers;
however, immune-related adverse events (irAEs) have been reported and the timing and …

[HTML][HTML] Anticancer Activity of Peganum harmala and Haloxylon salicornicum Leaf Extracts on Lung Cancer A549 and Prostate Cancer PC-3 Cell Lines

NM Alhawiti, WH Alramadhan, W Boadi… - American Journal of Plant …, 2023 - scirp.org
Cancer is a worldwide disease that ranks as the second-largest cause of death after
cardiovascular disease. In 2019, the estimated number of cancer deaths was around 10 …

Immune checkpoint targeting antibodies hold promise for combinatorial cancer therapeutics

Ritu, P Chandra, A Das - Clinical and Experimental Medicine, 2023 - Springer
Through improving the immune system's ability to recognize and combat tumor cells as well
as its receptivity to changes in the tumor microenvironment, immunotherapy has emerged as …

[HTML][HTML] Prevalence and Associated Factors for Thyroid Dysfunction Among Patients On Targeted Therapy for Cancers: A Single-Center Study from Thailand

K Chawalitmongkol, K Maneenil… - Journal of the ASEAN …, 2023 - ncbi.nlm.nih.gov
Prevalence and Associated Factors for Thyroid Dysfunction Among Patients On Targeted
Therapy for Cancers: A Single-Center Study from Thailand - PMC Back to Top Skip to main …

Isolated autoimmune adrenocorticotropic hormone deficiency: A positive predictor of survival among cancer patients treated with checkpoint inhibitors

S Aviv-Shimoni, I Uri, H Milloh-Raz, R Percik - Autoimmunity Reviews, 2023 - Elsevier
Objective We aimed to characterize cancer patients who developed isolated
adrenocorticotrophic hormone (ACTH) deficiency (IAD) after treatment with checkpoint …