CD1 displays its own negative regulators

A Shahine, I Van Rhijn, J Rossjohn… - Current Opinion in …, 2023 - Elsevier
After two decades of the study of lipid antigens that activate CD1-restricted T cells, new
studies show how autoreactive αβ T-cell receptors (TCRs) can directly recognize the outer …

Markers and makers of NKT17 cells

N Liman, JH Park - Experimental & Molecular Medicine, 2023 - nature.com
Invariant natural killer T (i NKT) cells are thymus-generated innate-like αβ T cells that
undergo terminal differentiation in the thymus. Such a developmental pathway differs from …

CAR-iNKT cells targeting clonal TCRVβ chains as a precise strategy to treat T cell lymphoma

AG Rowan, K Ponnusamy, H Ren, GP Taylor… - Frontiers in …, 2023 - frontiersin.org
Introduction Most T cell receptor (TCR) Vβ chain-expressing T cell lymphomas (TCL)
including those caused by Human T cell leukaemia virus type-1 (HTLV-1) have poor …

In silico identification and characterization of small molecule binding to the CD1d immunoreceptor

P Rathakrishnan, AC McShan - Journal of Biomolecular Structure …, 2023 - Taylor & Francis
CD1 immunoreceptors are a non-classical major histocompatibility complex (MHC) that
present antigens to T cells to elucidate immune responses against disease. The antigen …

[PDF][PDF] Assessing innate-like T-cell function in patients with cancer

EMG Jarvis - 2023 - ourarchive.otago.ac.nz
Prostate cancer is the second most common cancer in men worldwide. Although a number
of prostate-specific antigens exist, immunotherapies have yet to become a standard of care …