Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …

Dysregulation of the oncogenic transcription factor HOXA9 is a prominent feature for most
aggressive acute myeloid leukemia cases and a strong indicator of poor prognosis in …

The ever-increasing number of cancer cases and persistently high mortality underlines the
urgent need to acquire new perspectives for developing innovative therapeutic approaches …

Non-coding RNAs (ncRNAs) play a critical role in the entire body, and their mis-regulation is
often associated with disease. In parallel with the advances in high-throughput sequencing …

Simple Summary This study aimed to evaluate the potential of circular RNA (circRNA)
expression profiles for the early detection of chronic lymphocytic leukemia (CLL) using …

Background Histone deacetylase (HDAC) inhibitor-based therapeutic drug tolerance is a
major obstacle to glioblastoma (GBM) treatment. Meanwhile, non-coding RNAs have been …

Drug sensitivity is critical for enabling personalized treatment. Many studies have shown that
long non-coding RNAs (lncRNAs) are closely related to drug sensitivity because lncRNAs …

Background Acute myeloid leukemia (AML) is a highly heterogeneous cluster of
hematologic malignancies. Leukemic stem cells (LSCs) are one of the culprits for the …

Increasing evidence has displayed the vital influence of lncRNA in tumorigenesis and
chemoresistance of cancer treatment. This study investigated the function of lncRNA PTOV1 …

With the deepening of the genome project study, attention on noncoding RNAs is increasing.
Long noncoding RNAs (lncRNAs) have become a new research hotspot. A growing number …