IgE-mediated cow's milk protein allergy (CMPA) is one of the most prevalent food allergies in
early childhood. Though the cornerstone of management involves the strict avoidance of …

Allergen-specific immunotherapy (AIT) remains the only disease-modifying treatment for IgE-
mediated allergic diseases such as allergic rhinitis (AR). It can provide long-term clinical …

Introduction In allergic asthma patients, one of the more common phenotypes might benefit
from allergen immunotherapy (AIT) as add‐on intervention to pharmacological treatment …

There is good evidence for a role of T cells in food allergy, but there is a lack of mechanistic
understanding and phenotypic markers of the specific T cells contributing to pathology …

The immune system discriminates between harmful and harmless antigens based on past
experiences; however, the underlying mechanism is largely unknown. From the viewpoint of …

Allergic diseases occur due to a dysregulated immune system that is characterized by
inflammation and the formation of specific IgE antibodies against harmless environmental …

Anaphylaxis is a life-threatening or even fatal systemic hypersensitivity reaction. The
incidence of anaphylaxis has risen at an alarming rate in the past decades in the majority of …

Introduction: In allergic asthma patients, one of the more common phenotypes might benefit
from allergen immunotherapy (AIT) as add-on intervention to pharmacological treatment. AIT …

This dissertation could not have been possible without the support from many people.
Especially, I am thankful to Prof. Claudia Traidl-Hoffmann and PD Dr. Stefanie Gilles who …

Sažetak Alergenska imunoterapija (AIT) je jedino uzročno liječenje alergijskih bolesti čija je
učinkovitost i sigurnost dokazana u liječenju alergijskog rinitisa i astme u djece i odraslih …