The role of ERK1/2 pathway in the pathophysiology of Alzheimer's disease: an overview and update on new developments
Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide.
Several findings suggest that correcting the dysregulated signaling pathways may offer a …
Several findings suggest that correcting the dysregulated signaling pathways may offer a …
[HTML][HTML] The Amyloid Cascade Hypothesis 2.0 for Alzheimer's disease and aging-associated cognitive decline: From molecular basis to effective therapy
V Volloch, S Rits-Volloch - International Journal of Molecular Sciences, 2023 - mdpi.com
With the long-standing amyloid cascade hypothesis (ACH) largely discredited, there is an
acute need for a new all-encompassing interpretation of Alzheimer's disease (AD). Whereas …
acute need for a new all-encompassing interpretation of Alzheimer's disease (AD). Whereas …
Antioxidant and Antineuroinflammatory Mechanisms of Kaempferol-3-O-β-d-Glucuronate on Lipopolysaccharide-Stimulated BV2 Microglial Cells through the Nrf2 …
HJ Lim, R Prajapati, SH Seong, HA Jung, JS Choi - ACS omega, 2023 - ACS Publications
Aglycone-and glycoside-derived forms of flavonoids exist broadly in plants and foods such
as fruits, vegetables, and peanuts. However, most studies focus on the bioavailability of …
as fruits, vegetables, and peanuts. However, most studies focus on the bioavailability of …
[HTML][HTML] Next Generation Therapeutic Strategy for Treatment and Prevention of Alzheimer's Disease and Aging-Associated Cognitive Decline: Transient, Once-in-a …
V Volloch, S Rits-Volloch - International Journal of Molecular Sciences, 2023 - mdpi.com
Although the long-standing Amyloid Cascade Hypothesis (ACH) has been largely
discredited, its main attribute, the centrality of amyloid-beta (Aβ) in Alzheimer's disease (AD) …
discredited, its main attribute, the centrality of amyloid-beta (Aβ) in Alzheimer's disease (AD) …
Emerging roles of signal transduction pathways in neurodegenerative diseases. Hunting new possible therapeutic molecular targets
VR Lo Vasco - OBM Geriatrics, 2023 - iris.unimore.it
Illnesses following the degeneration of the nervous system can occur due to aging or
genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of …
genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of …
Diabetes and cognitive dysfunction
B Kim, C Sims-Robinson, SA Sakowski… - Neurobiology of Brain …, 2023 - Elsevier
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia. The two most
common types are type 1 and type 2 diabetes. Type 1 diabetes is often termed “juvenile …
common types are type 1 and type 2 diabetes. Type 1 diabetes is often termed “juvenile …
The Effects of Dexamethasone on Estrogen Cell Signaling Pathways in the mHippoE-14 Cell Line & Female Rats
S Dobronyi - 2023 - atrium.lib.uoguelph.ca
Previous research in our lab has demonstrated alterations in molecular markers of
hippocampal structure and function in response to stress, including DUSP6 expression, as …
hippocampal structure and function in response to stress, including DUSP6 expression, as …
Phosphodiesterase inhibitors and uses thereof
DW Landry, S Deng, O Arancio, J Fiorito… - US Patent …, 2023 - Google Patents
3,674,790 A 7/1972 Wolf et al. 4, 742061 A 5/1988 Martin et al. 4,816,464 A 3/1989 Gilman
et al. 4, 843079 A 6/1989 Shutske et al. 5.250. 534 A 10/1993 Bell et al. 5, 294612 A 3/1994 …
et al. 4, 843079 A 6/1989 Shutske et al. 5.250. 534 A 10/1993 Bell et al. 5, 294612 A 3/1994 …