Insight into the pivotal role of signaling pathways in psoriasis pathogenesis, potential therapeutic molecules and drug delivery approaches
Y Tomar, S Gorantla, G Singhvi - Drug discovery today, 2023 - Elsevier
Highlights•Psoriasis is a chronic inflammatory skin disorder affecting 125 million people
worldwide.•The intracellular pathways JAK-STAT, PDE4, S1P, A 3 AR and NF-κB have been …
worldwide.•The intracellular pathways JAK-STAT, PDE4, S1P, A 3 AR and NF-κB have been …
Immunosuppression by opioids: mechanisms of action on innate and adaptive immunity
Q Sun, Z Li, Z Wang, Q Wang, F Qin, H Pan… - Biochemical …, 2023 - Elsevier
Opioids are excellent analgesics for the clinical treatment of various types of acute and
chronic pain, particularly cancer-related pain. Nevertheless, it is well known that opioids …
chronic pain, particularly cancer-related pain. Nevertheless, it is well known that opioids …
Role of adenosine A2a receptor in cancers and autoimmune diseases
H Ye, J Zhao, X Xu, D Zhang, H Shen… - Immunity, Inflammation …, 2023 - Wiley Online Library
Adenosine receptors are P1 class of purinergic receptors that belong to G protein‐coupled
receptors. There are 4 subtypes of adenosine receptors, namely A1, A2A, A2B, and A3 …
receptors. There are 4 subtypes of adenosine receptors, namely A1, A2A, A2B, and A3 …
Navigating the landscape of psoriasis therapy: novel targeted pathways and emerging trends
S Innani, Y Tomar, V Rana… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Psoriasis is a chronic, inflammatory, non-communicable skin disorder that
affects a patient's social and emotional well-being. It is characterized by hyperproliferation of …
affects a patient's social and emotional well-being. It is characterized by hyperproliferation of …
Once Upon a Time Adenosine and Its Receptors: Historical Survey and Perspectives as Potential Targets for Therapy in Human Diseases
D Catarzi, F Varano, S Calenda, E Vigiani… - Purinergic Receptors and …, 2023 - Springer
Endogenous autacoid adenosine plays important physiological roles in various tissues and
organs by acting through A1, A2A, A2B, and A3 receptors. Dysregulated extracellular …
organs by acting through A1, A2A, A2B, and A3 receptors. Dysregulated extracellular …