The pathogenicity of L. pneumophila, the causative agent of Legionnaires' disease, depends
on an arsenal of interacting proteins. Here we describe how surface-associated and …

Flagellin is the cognate ligand for host pattern recognition receptors, toll-like receptor 5
(TLR5) in the cell surface, and NAIP5/NLRC4 inflammasome in the cytosol. TLR5-binding …

The 11 lytic transglycosylases of Pseudomonas aeruginosa have overlapping activities in
the turnover of the cell‐wall peptidoglycan. Rare lipoprotein A (RlpA) is distinct among the …

Pseudomonas aeruginosa is an opportunistic human pathogen responsible for acute and
chronic, hard to treat infections. Persistence of P. aeruginosa is due to its ability to develop …

In its simplest form, bacterial flagellar filaments are composed of flagellin proteins with just
two helical inner domains, which together comprise the filament core. Although this minimal …

Eukaryotes, archaea, and bacteria each independently evolved flagellar-based motility
systems allowing cells to swim in solution. The two prokaryotic flagellar systems involve the …

The recognition of pathogens by plants at the cell surface is crucial for activating plant
immunity. Plants employ pattern recognition receptors (PRRs) to detect microbe-associated …

Bacteria develop a variety of extracellular fibrous structures crucial for their survival, such as
flagella and pili. In this study, we use cryo-EM to identify protein fibrils surrounding lab …

Flagellar motility has independently arisen three times during evolution: in bacteria,
archaea, and eukaryotes. In prokaryotes, the supercoiled flagellar filaments are composed …

Flagella are dynamic, ion-powered machines with assembly pathways that are optimized for
efficient flagella production. In bacteria, dozens of genes are coordinated at specific times in …