New insights into the diagnosis and management of Stevens–Johnson syndrome and toxic epidermal necrolysis
Y Saito, R Abe - Current Opinion in Allergy and Clinical …, 2023 - journals.lww.com
The pathogenesis of SJS/TEN remains unclear and effective therapeutic agents have not yet
been established. As the involvement of innate immunity, such as monocytes and …
been established. As the involvement of innate immunity, such as monocytes and …
Why drug exposure is frequently associated with T-cell mediated cutaneous hypersensitivity reactions
J Line, E Saville, X Meng, D Naisbitt - Frontiers in Toxicology, 2023 - frontiersin.org
Cutaneous hypersensitivity reactions represent the most common manifestation of drug
allergy seen in the clinic, with 25% of all adverse drug reactions appearing in the skin. The …
allergy seen in the clinic, with 25% of all adverse drug reactions appearing in the skin. The …
[HTML][HTML] TNF-α‒Mediated keratinocyte expression and release of matrix metalloproteinase 9: Putative mechanism of pathogenesis in stevens‒johnson syndrome …
A Olsson-Brown, V Yip, ED Ogiji, C Jolly… - Journal of Investigative …, 2023 - Elsevier
Stevens‒Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are severe
cutaneous adverse drug reactions characterized by widespread keratinocyte cell death and …
cutaneous adverse drug reactions characterized by widespread keratinocyte cell death and …
Intravenous immunoglobulins, cyclosporine, and best supportive care in epidermal necrolysis: diverse effects on systemic inflammation
V Schmidt, S Lalevée, S Traidl, M Ameri, R Ziadlou… - Allergy, 2023 - Wiley Online Library
Abstract Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) are rare but potentially life‐threatening cutaneous adverse reactions. There is still no …
(TEN) are rare but potentially life‐threatening cutaneous adverse reactions. There is still no …
TNF‐α induced extracellular release of keratinocyte high‐mobility group box 1 in Stevens‐Johnson syndrome/toxic epidermal necrolysis: Biomarker and putative …
G Nwikue, A Olsson‐Brown… - The Journal of …, 2023 - Wiley Online Library
Decreased epidermal high‐mobility group box 1 (HMGB1) expression is an early marker of
epidermal injury in Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) …
epidermal injury in Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) …
APOA4 as a novel predictor of prognosis in Stevens-Johnson syndrome/toxic epidermal necrolysis: a proteomics analysis from two prospective cohorts
T Gong, P Zhang, SF Ruan, Z Xiao, W Chen… - Journal of the American …, 2023 - Elsevier
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are
rare but life-threatening adverse drug reactions. Conventional systemic therapies are of …
rare but life-threatening adverse drug reactions. Conventional systemic therapies are of …
Drug allergy in women
EY Lee, AM Copaescu, JA Trubiano, EJ Phillips… - The Journal of Allergy …, 2023 - Elsevier
Across all settings, adult females self-report more drug allergies than adult males. Although
there is epidemiological evidence of increased drug allergy labeling in post-pubertal …
there is epidemiological evidence of increased drug allergy labeling in post-pubertal …
Ocular Manifestations and Outcomes in Children With Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Comparison With Adult Patients
YL Chen, TY Tsai, LY Pan, YJ Tsai, SY Chen… - American Journal of …, 2023 - Elsevier
PURPOSE To compare the clinical features and visual outcomes in children and adults with
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). DESIGN …
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). DESIGN …
Drug-induced Stevens Johnson syndrome and toxic epidermal necrolysis: Interpreting the systematic reviews on immunomodulatory therapies
BYH Thong - Asia Pacific Allergy, 2023 - journals.lww.com
Abstract Drug-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) are non-immunoglobulin E-mediated severe cutaneous adverse reactions with a high …
(TEN) are non-immunoglobulin E-mediated severe cutaneous adverse reactions with a high …
Biologic TNF-α inhibitors for Stevens–Johnson Syndrome, toxic epidermal necrolysis, and TEN-SJS overlap: a study-level and patient-level meta-analysis
J Cao, X Zhang, X Xing, J Fan - Dermatology and Therapy, 2023 - Springer
Abstract Introduction Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) are severe cutaneous adverse reactions with high morbidity and mortality and not …
(TEN) are severe cutaneous adverse reactions with high morbidity and mortality and not …