[HTML][HTML] When blood pressure refuses to budge: exploring the complexity of resistant hypertension
MK Champaneria, RS Patel, TL Oroszi - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Resistant hypertension, defined as blood pressure that remains above goal despite using
three or more antihypertensive medications, including a diuretic, affects a significant …
three or more antihypertensive medications, including a diuretic, affects a significant …
[HTML][HTML] Sex-specific features of the correlation between GWAS-noticeable polymorphisms and hypertension in Europeans of Russia
The aim of the study was directed at studying the sex-specific features of the correlation
between genome-wide association studies (GWAS)-noticeable polymorphisms and …
between genome-wide association studies (GWAS)-noticeable polymorphisms and …
[HTML][HTML] Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure
W Wang, J Yao, W Li, Y Wu, H Duan, C Xu, X Tian… - Clinical …, 2023 - Springer
Background Hypertension is a crucial risk factor for developing cardiovascular disease and
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …
[HTML][HTML] Risk Effects of rs1799945 Polymorphism of the HFE Gene and Intergenic Interactions of GWAS-Significant Loci for Arterial Hypertension in the Caucasian …
T Ivanova, M Churnosova, M Abramova… - International Journal of …, 2023 - mdpi.com
The aim of this case-control replicative study was to investigate the link between GWAS-
impact for arterial hypertension (AH) and/or blood pressure (BP) gene polymorphisms and …
impact for arterial hypertension (AH) and/or blood pressure (BP) gene polymorphisms and …
[HTML][HTML] Genome-wide association studies of retinal vessel tortuosity identify numerous novel loci revealing genes and pathways associated with ocular and …
M Tomasoni, MJ Beyeler, SO Vela, N Mounier… - Ophthalmology …, 2023 - Elsevier
Purpose To identify novel susceptibility loci for retinal vascular tortuosity, to better
understand the molecular mechanisms modulating this trait, and reveal causal relationships …
understand the molecular mechanisms modulating this trait, and reveal causal relationships …
[HTML][HTML] Systematic characterization of regulatory variants of blood pressure genes
W Oliveros, K Delfosse, DF Lato, K Kiriakopulos… - Cell Genomics, 2023 - cell.com
High blood pressure (BP) is the major risk factor for cardiovascular disease. Genome-wide
association studies have identified genetic variants for BP, but functional insights into …
association studies have identified genetic variants for BP, but functional insights into …
Ultra-high dimensional quantile regression for longitudinal data: an application to blood pressure analysis
Despite major advances in research and treatment, identifying important genotype risk
factors for high blood pressure remains challenging. Traditional genome-wide association …
factors for high blood pressure remains challenging. Traditional genome-wide association …
Maternal and placental ANRIL polymorphisms and preeclampsia susceptibility
M Asadi-Tarani, M Saravani, M Ghasemi… - Personalized …, 2023 - Taylor & Francis
Aim: The possible effects of maternal and placental ANRIL polymorphisms on preeclampsia
were examined. Methods: The maternal blood of 315 preeclamptic and 317 control women …
were examined. Methods: The maternal blood of 315 preeclamptic and 317 control women …
Hypertension as a novel link for shared heritability in age at menarche and cardiometabolic traits
Context Extremely early age at menarche, also called precocious puberty, has been
associated with various cardiometabolic traits, but their shared heritability remains unclear …
associated with various cardiometabolic traits, but their shared heritability remains unclear …
Genetic Variants of Adrenoceptors
A Ahles, S Engelhardt - 2023 - Springer
Adrenoceptors are class A G-protein-coupled receptors grouped into three families (α1-, α2-,
and β-adrenoceptors), each one including three members. All nine corresponding …
and β-adrenoceptors), each one including three members. All nine corresponding …