[HTML][HTML] When blood pressure refuses to budge: exploring the complexity of resistant hypertension

MK Champaneria, RS Patel, TL Oroszi - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Resistant hypertension, defined as blood pressure that remains above goal despite using
three or more antihypertensive medications, including a diuretic, affects a significant …

[HTML][HTML] Sex-specific features of the correlation between GWAS-noticeable polymorphisms and hypertension in Europeans of Russia

T Ivanova, M Churnosova, M Abramova… - International Journal of …, 2023 - mdpi.com
The aim of the study was directed at studying the sex-specific features of the correlation
between genome-wide association studies (GWAS)-noticeable polymorphisms and …

[HTML][HTML] Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure

W Wang, J Yao, W Li, Y Wu, H Duan, C Xu, X Tian… - Clinical …, 2023 - Springer
Background Hypertension is a crucial risk factor for developing cardiovascular disease and
reducing life expectancy. We aimed to detect DNA methylation (DNAm) variants potentially …

[HTML][HTML] Risk Effects of rs1799945 Polymorphism of the HFE Gene and Intergenic Interactions of GWAS-Significant Loci for Arterial Hypertension in the Caucasian …

T Ivanova, M Churnosova, M Abramova… - International Journal of …, 2023 - mdpi.com
The aim of this case-control replicative study was to investigate the link between GWAS-
impact for arterial hypertension (AH) and/or blood pressure (BP) gene polymorphisms and …

[HTML][HTML] Genome-wide association studies of retinal vessel tortuosity identify numerous novel loci revealing genes and pathways associated with ocular and …

M Tomasoni, MJ Beyeler, SO Vela, N Mounier… - Ophthalmology …, 2023 - Elsevier
Purpose To identify novel susceptibility loci for retinal vascular tortuosity, to better
understand the molecular mechanisms modulating this trait, and reveal causal relationships …

[HTML][HTML] Systematic characterization of regulatory variants of blood pressure genes

W Oliveros, K Delfosse, DF Lato, K Kiriakopulos… - Cell Genomics, 2023 - cell.com
High blood pressure (BP) is the major risk factor for cardiovascular disease. Genome-wide
association studies have identified genetic variants for BP, but functional insights into …

Ultra-high dimensional quantile regression for longitudinal data: an application to blood pressure analysis

T Zu, H Lian, B Green, Y Yu - Journal of the American Statistical …, 2023 - Taylor & Francis
Despite major advances in research and treatment, identifying important genotype risk
factors for high blood pressure remains challenging. Traditional genome-wide association …

Maternal and placental ANRIL polymorphisms and preeclampsia susceptibility

M Asadi-Tarani, M Saravani, M Ghasemi… - Personalized …, 2023 - Taylor & Francis
Aim: The possible effects of maternal and placental ANRIL polymorphisms on preeclampsia
were examined. Methods: The maternal blood of 315 preeclamptic and 317 control women …

Hypertension as a novel link for shared heritability in age at menarche and cardiometabolic traits

HY Fan, KL Chien, YT Huang, JBK Hsu… - The Journal of …, 2023 - academic.oup.com
Context Extremely early age at menarche, also called precocious puberty, has been
associated with various cardiometabolic traits, but their shared heritability remains unclear …

Genetic Variants of Adrenoceptors

A Ahles, S Engelhardt - 2023 - Springer
Adrenoceptors are class A G-protein-coupled receptors grouped into three families (α1-, α2-,
and β-adrenoceptors), each one including three members. All nine corresponding …